Join A SkinDepth Convo with Lira Clinical founders and skincare experts, Metaxia Dalikas and Francine Kagarakis. A show dedicated to educating and inspiring all those in the skincare industry and also for those of you interested in finding ways to improve yourself from the inside out. In each episode the show covers the latest skincare trends, scientific skincare protocols and ingredient technology to prevent and treat skin conditions including acne, pigmentation, rosacea and more. The show also focuses on the science behind anti-aging and maintaining ageless skin. Get tips on prevention and maintaining flawless skin and enjoy some entertaining conversation along the way. Have questions about skincare? We answer questions from listeners in every show. Submit your questions to skindepthconvo@liraclinical.com
Skin Depth Ep 70 – September 21, 2026 – EXO-tech: Breakthrough Delivery Technology
What makes a great skincare formula truly effective? It’s not just what’s in it; it’s how those ingredients are delivered.
In this episode of A SkinDepth Convo, Lira Clinical founders Metaxia Dalikas and Francine Kagarakis, along with Anna Kagarakis, are joined by the Lira Clinical Education Team, Tiffany Fraedrich and Alex Vetterlein, to explore the science behind EXO-tech™, Lira Clinical’s umbrella of advanced delivery technologies.
From PDRN and peptides to NAD+ and growth factors, today’s most innovative actives can present unique challenges involving stability, molecular size, and skin compatibility. The team breaks down how advanced delivery technology helps address these challenges, allowing ingredients to remain stable and perform effectively at the right target and the right time.
Discover why two formulas featuring the same trending ingredient can perform very differently, how delivery technology influences formulation, and why Lira Clinical continues to rethink the way advanced actives are incorporated into professional skincare.
Because innovation isn’t just about discovering the next breakthrough ingredient, it’s about creating the technology that helps it perform.
4 Aug 2026
Skin Depth Ep 69 – August 4, 2026 – Signal, Deliver, Regenerate: The Latest Science in Skin Renewal ft The Wildtype Team
When new skincare technology emerges, questions naturally follow, and understanding the science is just as important as seeing the results.
In this episode of A SkinDepth Convo, Lira Clinical founders Metaxia Dalikas and Francine Kagarakis speak with Dr. Aryé Elfenbein, Co-Founder of Wildtype, and Dr. Larry Weiss, Co-Founder and Managing Director of BiomeMimetics, LLC. Together, they reveal the science behind Marine Cellular Complex, also known as Wild Salmon Stem Cell Conditioned Media—the innovative regenerative technology featured in Lira Clinical’s new REGEN Line.
What gives this Marine Cellular Complex four times greater regenerative power than PDRN alone? Tune in to uncover the research, including increased collagen and elastin production, reduced markers of inflammation, and powerful support for the skin’s natural renewal processes, and discover why this technology could represent a new frontier in professional skincare.
12 Jun 2026
Skin Depth Ep 68 – June 12, 2026 – A PDRN Revolution
The future of regenerative skincare is here.
Join Metaxia, Francine, and Anna as they pull back the curtain on the launch of REGEN Line, Lira Clinical’s groundbreaking new collection designed to support skin recovery, renewal, and long-term skin health.
In this special episode, they explore the science behind two buzzworthy innovations: PDRN and Wild Salmon Stem Cell-CM, and discuss how these advanced ingredients are transforming both professional treatments and home care. From concept to clinical application, get an exclusive look at the research, technology, and vision driving the next evolution of skincare.
If you’ve been hearing the excitement around regenerative aesthetics, this is the episode you won’t want to miss.
Reach and audience
Public platform figures. Ratings count people who left a rating, not total listeners.
YouTube views
236,453
Score snapshot 15 Sept 2025
Apple Podcasts (US)
4.9 / 5
20 ratings
Spotify
5.0 / 5
5 ratings
Podcast Authority Score: 65 / 100
A composite of feed quality, social presence, YouTube performance and engagement. Read the methodology.
Quality
62
Social presence
0
YouTube
86
Engagement
85
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