Join A SkinDepth Convo with Lira Clinical founders and skincare experts, Metaxia Dalikas and Francine Kagarakis. A show dedicated to educating and inspiring all those in the skincare industry and also for those of you interested in finding ways to improve yourself from the inside out. In each episode the show covers the latest skincare trends, scientific skincare protocols and ingredient technology to prevent and treat skin conditions including acne, pigmentation, rosacea and more. The show also focuses on the science behind anti-aging and maintaining ageless skin. Get tips on prevention and maintaining flawless skin and enjoy some entertaining conversation along the way. Have questions about skincare? We answer questions from listeners in every show. Submit your questions to skindepthconvo@liraclinical.com

Lira Clinical Podcast - A SkinDepth Convo
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Podcast Overview
Join A SkinDepth Convo with Lira Clinical founders and skincare experts, Metaxia Dalikas and Francine Kagarakis. A show dedicated to educating and inspiring all those in the skincare industry and also for those of you interested in finding ways to improve yourself from the inside out. In each episode the show covers the latest skincare trends, scientific skincare protocols and ingredient technology to prevent and treat skin conditions including acne, pigmentation, rosacea and more. The show also focuses on the science behind anti-aging and maintaining ageless skin. Get tips on prevention and maintaining flawless skin and enjoy some entertaining conversation along the way. Have questions about skincare? We answer questions from listeners in every show. Submit your questions to skindepthconvo@liraclinical.com
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Publishing Since
1/17/2020
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Recent Episodes

May 18, 2026
Skin Depth Ep 67 – May 18, 2026 – Wildtype & Lira Clinical: A Revolution in PDRN ft The WildType Team
<p>In this groundbreaking episode of A SkinDepth Convo, hosts Metaxia Dalikas, Francine Kagarakis, and Anna Kagarakis are joined by the Wildtype team for an in-depth conversation on how biotechnology and regenerative science are transforming the future of skincare.</p><p></p><p>Together, they explore the evolution of next-generation ingredients, from the growing interest in PDRN to Wildtype’s breakthrough innovation: Marine Cellular Complex, also known as Wild Salmon Stem Cell Conditioned Media. The discussion dives into the science behind cultivated salmon technology, how it has expanded beyond food innovation into advanced skincare applications, and what this means for the future of skin health and regeneration.</p><p></p><p>This episode also highlights a true San Francisco Bay Area collaboration, bringing together visionary leaders in biotechnology and professional skincare to discuss what’s real, what’s next, and how science-backed advancements are redefining the industry. If you’re curious about regenerative ingredients, cutting-edge skincare science, and the intersection of biotech and beauty, this is a conversation you won’t want to miss.</p>

April 13, 2026
Skin Depth Ep 66 – April 13, 2026 – The Wellness Series: Virtual Fasting & The Magnificent Free 7 ft Dr. John Konstantin
<p>In this episode of A SkinDepth Convo, hosts Metaxia Dalikas, Francine Kagarakis, and Anna Kagarakis explore the powerful connection between internal health and skin health, revealing why true radiance starts from within.</p><p></p><p>From the role of the microbiome to liver function and cellular renewal, the conversation dives into how the body’s internal systems directly influence the skin’s appearance, resilience, and overall vitality. Drawing from their deep expertise and experience as founders of Lira Clinical, the hosts discuss the growing integration of wellness, esthetics, and medical science, and why modern skincare is no longer just skin-deep.</p><p></p><p>They are joined by special guest Dr. John Konstantin, who helps connect the dots between internal health and lasting, visible skin results. Together, they unpack how a holistic, inside-out approach is shaping the future of skincare and empowering both professionals and clients to think beyond the surface.</p><p></p><p>Tune in to discover how aligning internal wellness with advanced skincare can transform not just your skin, but your overall health.</p><p></p>

December 31, 2025
Skin Depth Ep 65 – December 31, 2025 – Purely Clinical 2025 Recap
Purely Clinical is more than an event; it’s an experience where education meets innovation and the future of skincare takes shape.Over the past year, the Lira Clinical owners traveled across the globe delivering advanced education, protocol-driven learning, and exclusive first looks at upcoming innovations, straight to the treatment room. We’re recapping standout moments from the tour stops and unpacking what attendees truly gained, from interactive sessions and protocol development to testing prototypes and influencing product launches before they hit the market.And of course, we’re teasing what’s ahead, because Purely Clinical 2026 is already shaping up to be something special. Join expert hosts and Lira Clinical founders Metaxia Dalikas and Francine Kagarakis for an inside look at the experience that’s redefining clinical education.
68 total episodes available
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- What is Lira Clinical Podcast - A SkinDepth Convo?
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This podcast updates bi-weekly.
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This podcast is available on 8 platforms including Apple Podcasts, Spotify, and more. You can also use the RSS feed directly.
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Yes, this podcast regularly features guests.
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