New findings from the OVERCOME study show that improving or worsening migraine status can have a major impact on our work lives, quality of life, stigma, and treatment needs. Molly O'Brien (mailto:mollyjobrien@gmail.com) breaks it down in this Migraine Minute News Update.
Read the study: https://bit.ly/4h9NkTJ
SCRIPT
New information from the OVERCOME study shows how improving or worsening migraine-related symptoms can affect other areas of our lives.
The recent analysis looked at data from more than 11 thousand people with migraine over the course of a year. Based on monthly headache days, migraine-related disability, and quality of life, participants noted if migraine improved, worsened, or showed no change.
Just over 40 percent said overall…migraine improved. About 24 percent said migraine worsened and about 35 percent said no change.
The migraine improved group saw other benefits:
Improved work productivity, less migraine stigma, better physical function, improved health-related quality of life. And they were less likely to overuse acute medications.
Those whose migraine worsened saw an increase in monthly headache days and greater migraine-related disability. Migraine had a more of a negative impact on their work, and they had an increase in need for acute and preventive medication.
18 Sept 2026
Does Fertility Treatment Have an Impact on Headache?
Could fertility treatment affect migraine and headache? A new review of more than 100 studies, published in the Journal of Headache and Pain, finds headache may be an overlooked and understudied side effect of fertility treatments. Molly O'Brien has more details in this Migraine Minute News Update.
Read The Source: bit.ly/4hAFO6j (https://bit.ly/4hAFO6j)
Creative Commons: https://creativecommons.org/licenses/by/4.0/
Script: A new review draws attention to migraine and headache as a potentially overlooked side effect of fertility treatment. Researchers reviewed more than 100 studies involving the relationship between fertility treatment and headache, in people with and without pre-existing headache disorders.
They found headache was reported with several treatment approaches, including different hormone therapies, ovulation induction, and IVF. But the reported rates of headache and migraine varied widely from study to study.
Researchers say people with a history of migraine may see a higher risk of severe headache during fertility treatment. But evidence is still inconsistent.
The big takeaway? Researchers found that even though some FDA- and EMA-approved fertility drugs list headache or migraine as a common side effect, it seems there is no standardized reporting on any symptom details.
Because headache and migraine are common in women of reproductive age, researchers say future studies should look at headache type, report timing and intensity, and consider other factors.
4 Sept 2026
VA Expands Migraine Treatment Options for Veterans
The US Department of Veterans Affairs will now cover the use of at-home neuromodulation devices for migraine and depression. Molly O'Brien has details in this Migraine Minute News Update. Read More: https://bit.ly/4bKB9uO
Script: More treatment options for US Veterans with migraine and/or depression are now available and covered by the VA. This is promising news, as migraine and depression are some of the most common health conditions treated in the VA health system, with more than half a million veterans diagnosed with migraine in the VA.
Neuroscience medical technology company Neurolief announced in a press release that two of their prescription neuromodulation therapies will be covered and available for at-home use through the Department of Veterans Affairs.
Relivion MG for the acute treatment of migraine and ProlivRx for adults with major depressive disorder who have not achieved adequate relief from antidepressants.
A study published in Headache showed Relivion MG to be safe and effective for acute treatment. In the study, 46 percent of those who used Relivion MG were pain-free at the two-hour mark compared with about 12 percent who used a sham device.
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