This is a professional development podcast dedicated to helping veterinarians and veterinary students discover and impliment the habits and routines necessary to develop professionally and personally.

Operators To OWNERS
Claim This Podcastby Eric R
Podcast Overview
This is a professional development podcast dedicated to helping veterinarians and veterinary students discover and impliment the habits and routines necessary to develop professionally and personally.
Language
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Publishing Since
7/30/2019
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Recent Episodes

June 2, 2023
OTO Episode 77: What Are You Master Of?
<p> On today's thoughts from the truck episode, I ponder a little bit about a quote and this quote, for a context comes from one of my top seven of all time books; biggest, most impactful books that I have read. One of these books, out of the seven, that lie on my mind altering, life altering type shelf at home.</p> <p><br></p> <p>This book is called High Performance Habits by Brendan Burchart. Highly recommend reading this book and looking into it, but in this book, the author, who is a self-help, self-development type guru selected a quote from Andrew Carnegie, and if you don't know who Andrew is, he was an industrialist specifically within the steel industry or on the turn of the century, and Andrew was credited with saying:</p> <p><br></p> <p>"I believe the true road to pre-eminent success in any line is to make yourself master in that line." </p> <p><br></p> <p>Today we will discuss why mastery is intrinsically rewarding to us and how we can begin to capture our own small chunk of it on a daily basis!</p>

April 27, 2023
The Cutting Edge - Article 32 - Using Saccharomyces cerevisiae to reduce BRSV infection severity in neonatal calves via immune modulation
<p>Supplementing a Saccharomyces cerevisiae fermentation product modulates innate immune function and ameliorates bovine respiratory syncytial virus infection in neonatal calves</p> <p> Link: https://pubmed.ncbi.nlm.nih.gov/32780814/</p> <p>Ultimate Message:</p> <p>We do have an ability to modulate immune responses to make them less damaging within the respiratory tract of our calves and potentially beyond that if you start to look outside of this study. </p> <p>Big 3 Take Aways:</p> <p>Number one, there are differences between prebiotics, probiotics, and postbiotics. Is one necessarily better than the other? Do you need one more than the other? Not necessarily, but the ability of the postbiotics to be more concentrated versus diluted in what you'll see as the prebiotic and the probiotic potentially has a bigger impact than those other two factors and is worth considering when you're considering your source or your dollar investment for your clients. </p> <p>Number two, innate training. We can train the immune system to respond in a less destructive way, to just respond in a more phagocytic way versus more of kind of that nuclear bomb or uncontrolled damage type of way. That's very interesting that we have the ability to do that. </p> <p>Number three, we have the ability to control inflammation. And that again, ties into the response we get. We have less free oxygen oxidative species going out there, less oxidative bursts occurring, less overall damage and destruction to the overall airways.</p> <p>Abstract:</p> <p>The objectives of this study were to determine the effects of oral supplementation with Saccharomyces cerevisiae fermentation products on immune function and bovine respiratory syncytial virus (BRSV) infection in preweaned dairy calves. Twenty-four Holstein × Angus, 1- to 2-d-old calves (38.46 ± 0.91 kg initial body weight [BW]) were assigned two treatment groups: control or SCFP treated, milk replacer with 1 g/d SCFP (SmartCare) and calf starter top-dressed with 5 g/d SCFP (NutriTek). The study consisted of one 31-d period. On days 19 to 21 of the supplementation period, calves were challenged via aerosol inoculation with BRSV strain 375. Calves were monitored twice daily for clinical signs, including rectal temperature, cough, nasal and ocular discharge, respiration effort, and lung auscultation. Calves were euthanized on day 10 postinfection (days 29 to 31 of the supplementation period) to evaluate gross lung pathology and pathogen load. Supplementation with SCFP did not affect BW (P = 0.762) or average daily gain (P = 0.750), percentages of circulating white blood cells (P < 0.05), phagocytic (P = 0.427 for neutrophils and P = 0.460 for monocytes) or respiratory burst (P = 0.119 for neutrophils and P = 0.414 for monocytes) activity by circulating leukocytes either before or following BRSV infection, or serum cortisol concentrations (P = 0.321) after BRSV infection. Calves receiving SCFP had reduced clinical disease scores compared with control calves (P = 0.030), reduced airway neutrophil recruitment (P < 0.002), reduced lung pathology (P = 0.031), and a reduced incidence of secondary bacterial infection. Calves receiving SCFP shed reduced virus compared with control calves (P = 0.049) and tended toward lower viral loads in the lungs (P = 0.051). Immune cells from the peripheral blood of SCFP-treated calves produced increased (P < 0.05) quantities of interleukin (IL)-6 and tumor necrosis factor-alpha in response to toll-like receptor stimulation, while cells from the bronchoalveolar lavage (BAL) of SCFP-treated calves secreted less (P < 0.05) proinflammatory cytokines in response to the same stimuli. Treatment with SCFP had no effect on virus-specific T cell responses in the blood but resulted in reduced (P = 0.045) virus-specific IL-17 secretion by T cells in the BAL. Supplementing with SCFP modulates both systemic and mucosal immune responses and may improve the outcome of an acute respiratory viral infection in preweaned dairy calves. </p>

March 6, 2023
OTO Episode 76: Stress Makes You Dumber
Find the full article text at otovets.com/post/feeling-dumber-you-might-be-stressed Stress makes you dumber. Period. Our brains have a limited amount of working memory in them. As such our brain seeks to utilize this limited resource in the most effective way. This means that when we are stressed the brain begins to shift blood to prepare us for action. A natural and necessary response from an evolutionary perspective. The shift allows us to prepare for using this memory to aid our fight or flight centers aka limbic system. However, this blood must come from somewhere. That somewhere is the prefrontal cortex. Responsible for conscious creative thought and critical thinking, the prefrontal cortex, or P F C, is the contemplative part of our brain. It allows us to appraise a situation rather than to simply react to stimuli. Thus, the simple of act of becoming stressed means we are less physically able to critically think our way out of the problem.
109 total episodes available
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