Hosted by two Stanford graduate students, Neha and Elsa, Second Order explores the mental models and skills that make us better entrepreneurs. Through deep conversations with experts who’ve built, led, or studied what actually works, we go beyond the highlight reel to unpack the habits, frameworks, and decisions that drive meaningful impact. If you're building something (or thinking about it) this is your space to think a layer deeper.

Second Order
Claim This Podcastby Neha Balamurugan, Elsa Bismuth
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Podcast Overview
Hosted by two Stanford graduate students, Neha and Elsa, Second Order explores the mental models and skills that make us better entrepreneurs. Through deep conversations with experts who’ve built, led, or studied what actually works, we go beyond the highlight reel to unpack the habits, frameworks, and decisions that drive meaningful impact. If you're building something (or thinking about it) this is your space to think a layer deeper.
Language
🇺🇲
Publishing Since
5/28/2025
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Recent Episodes

November 10, 2025
From Scrubs to Startups: Why Doctors Choose to Build
<p>In this episode, <strong>Dr. Derek Paul</strong>, physician-turned-founder and CEO of <strong>Glass Health</strong>, joins <strong>Elsa</strong> to discuss the mindset shift from medicine to entrepreneurship—and how clinical reasoning can shape the way we build AI. Backed by <strong>Y Combinator</strong> and <strong>Breyer Capital</strong>, Glass Health began as a digital notebook for doctors and evolved into a leading platform for AI-powered clinical decision support.</p><p>Derek explains how physicians’ structured approach to diagnosis—testing hypotheses, managing uncertainty, and learning from feedback—translates directly into effective product design and company building. He shares how Glass ensures <strong>medical accuracy and safety</strong>, what it means to <strong>train AI models with physician expertise</strong>, and how startups can navigate <strong>FDA frameworks, EHR integrations, and data compliance</strong> while maintaining speed and innovation.</p><p>From leaving the clinic to leading an AI company, Derek reflects on the cognitive frameworks that drive both good medicine and good startups—and why mastering uncertainty is the core skill behind both.</p>

October 27, 2025
From Code to Care: How AI Is Transforming Modern Medicine
<p>In this episode, we sit down with <strong>Dr. Matt Lungren</strong>, Chief Scientific Officer at <strong>Microsoft Health & Life Sciences</strong> and former Stanford radiologist, to explore how <strong>AI is truly reshaping healthcare—beyond the buzzwords</strong>.</p><p><br></p><p>We discuss how Microsoft’s new <strong>multi-agent orchestration frameworks</strong> could change the game for hospitals—turning tools like Teams into intelligent ecosystems where agents collaborate across radiology, pathology, and clinical trials. Matt breaks down why <strong>integration now matters more than innovation</strong>, how <strong>startups can avoid building “features” instead of products</strong>, and what it really takes to cross the “last mile” into hospital deployment.</p><p><br></p><p>The conversation goes deep on <strong>AI governance, compliance, and the future of agentic systems</strong>, while offering blunt, practical advice for entrepreneurs: why raising capital isn’t a milestone, why distribution is everything, and how to know if you’ve built something users can’t live without.</p><p><br></p><p>From <strong>wearables and precision medicine</strong> to <strong>personalized therapies and real-time data</strong>, this episode reveals where the next decade of healthcare AI is headed—and how founders, clinicians, and technologists can shape it.</p>

October 14, 2025
Building in Clusters: Elad Gil on Career Strategy, the role of a CEO, and AI's Next Frontier
<p>What separates careers that plateau from those that keep accelerating? Elad Gil has some surprising answers.</p><p>Today's guest is Elad Gil, serial entrepreneur, investor, and author who's been at the center of Silicon Valley's biggest shifts for over two decades. We explore why location and industry clusters matter more than most people realize, how the best CEOs adapt their leadership as companies scale, and which emerging technology sector could be poised for a major breakthrough.</p><p>Elad shares why some of his best investments defied conventional wisdom, what trips up even experienced founders as they grow their companies, and how regulatory challenges in one industry offer unexpected lessons for another. We also discuss the balance between following themes and staying open to opportunities you didn't see coming.</p><p>Whether you're building a company or just trying to make smarter career moves, this episode offers practical frameworks you can use right away.</p>
6 total episodes available
Recent guests on Second Order
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Keegan Cooke
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Christina Wodtke
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- What is Second Order?
- How often does this podcast release new episodes?
This podcast updates daily.
- Where can I listen to this podcast?
This podcast is available on 4 platforms including Apple Podcasts, Spotify, and more. You can also use the RSS feed directly.
- Does this podcast accept guests?
Yes, this podcast regularly features guests.
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