The Interventional Endoscopist
Claim This Podcastby Mankanwal Sachdev
Podcast Overview
<p>Interventional endoscopy is moving fast. Join Phoenix-based interventional endoscopist Dr. Mankanwal Sachdev as he sits down with some of the brightest minds in GI to unpack new technologies, push the boundaries of therapeutic endoscopy, and tackle the real-world issues shaping the field.</p>
Language
🇺🇲
Publishing Since
3/16/2023
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Recent Episodes
June 25, 2026
Episode 44: The one where I discuss all things Speedboat/Creo with Dr. Davinderbir S. Pannu
In this episode of The Interventional Endoscopist, host Dr. Vinkaval Satdev sits down with Dr. Davinderbir Singh Pannu, a recognized leader in advanced therapeutic endoscopy at McLeod Health. For years, Endoscopic Submucosal Dissection (ESD) has been the gold standard for en bloc resection of complex mucosal lesions, but steep learning curves and equipment limitations have kept it centralized in major academic hubs. Dr. Pannu shares his journey of building a high-volume third-space endoscopy program (performing 80–100 cases a year) in a regional health system, saving patients from traveling hours for advanced care. Dive deep into the physics, economics, and clinical application of next-generation electrosurgical platforms. Dr. Satdev and Dr. Pannu break down the transition from traditional monopolar energy to multimodal bipolar microwave platforms—specifically focusing on the Creo Medical Chroma system with the Speedboat device. Key Takeaways: The Physics of Safety: How bipolar microwave energy limits collateral tissue damage and minimizes delayed perforations compared to traditional monopolar units. Tactile & Operational Shifts: Mastering pure cut currents, managing tissue resistance variations, and optimizing scope control. The Business Case for Advanced Tech: Navigating Value Analysis Committees (VAC), tracking downstream revenue, and proving ROI to hospital administrators. Clinical Humility & Career Growth: Dr. Pannu’s approach to mastering one major new technical skill every single year. Note: This podcast is completely independent and is not sponsored by any device company.
March 12, 2026
Episode 43: The one where I discuss all things Fractyl with Dr. Harith Rajagopalan
Resetting the Metabolic Setpoint: Duodenal Mucosal Resurfacing (DMR) and the Future of Obesity Care with Dr. Harith Rajagopalan Is the duodenum the "early warning beacon" for metabolic disease? In this episode, we sit down with Dr. Harith Rajagopalan, MD, PhD, Co-Founder and CEO of Fractyl Health, to discuss the revolutionary shift from treating downstream symptoms of diabetes and obesity to addressing the upstream root cause in the gut. We dive deep into the science and technique of Duodenal Mucosal Resurfacing (DMR)—an automated, 45-minute endoscopic outpatient procedure designed to reset the metabolic setpoint. Dr. Rajagopalan explains how high-fat, high-sugar diets pathologically alter the duodenal mucosa and how "resurfacing" this tissue can provide a durable off-ramp for patients on GLP-1 therapies. Key highlights include: The "Reset" Mechanism: How the duodenum acts as the body's nutrient-sensing center and why it becomes dysfunctional. Technical Deep Dive: A look at the automated circumferential saline injection and thermal ablation process (and the future of through-the-scope devices). The "Remain" Trial Data: Breakthrough insights into post-GLP-1 weight maintenance and craving reduction. The Rejuva Platform: A look at the first-in-class EUS-guided gene therapy targeting the pancreas. Whether you are a fellow learning the ropes or an attending looking for the next frontier in interventional GI, this episode explores a future where endoscopists own the management of metabolic disease.
February 26, 2026
Episode 42: The one where I discuss Endobariatrics and Endometabolic Endoscopy
In this episode, I explore the rapidly evolving world of Endobariatrics. As a bridge between lifestyle intervention and invasive surgery, these endoscopic procedures are fundamentally changing how I look at metabolic health and weight loss. In this episode, I discuss: Why I see endobariatrics as the "middle ground" for weight loss. My breakdown of Endometabolic Endoscopy and its impact on Type 2 Diabetes. Identifying the ideal candidate for these "incision-less" interventions. My thoughts on the future of gut-brain signaling and metabolic care. Whether you are a healthcare professional or someone curious about modern weight-loss tech, join me for a comprehensive look at the tools shaping the next decade of medicine. Listen here: https://bit.ly/TheIE-Ep42
44 total episodes available
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- What is The Interventional Endoscopist?
<p>Interventional endoscopy is moving fast. Join Phoenix-based interventional endoscopist Dr. Mankanwal Sachdev as he sits down with some of the brightest minds in GI to unpack new technologies, push the boundaries of therapeutic endoscopy, and tackle the real-world issues shaping the field.</p> - How often does this podcast release new episodes?
This podcast updates bi-weekly.
- Where can I listen to this podcast?
This podcast is available on 10 platforms including Apple Podcasts, Spotify, and more. You can also use the RSS feed directly.
- Does this podcast accept guests?
Yes, this podcast regularly features guests.
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