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Vascular Adviser Podcast

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by Vascular Adviser Team

8 episodes

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Podcast Overview

The audio files provided on the Thrombosis Adviser channel are intended for viewers outside the USA and the UK only. Thrombosis Adviser is an online resource for physicians and patients about current and emerging therapies for thromboembolic disease including venous thrombosis (VTE), atrial fibrillation (AF), and acute coronary syndrome (ACS). The Thrombosis Adviser podcast series is intended to provide information to HPCs. Imprint Published by: Bayer AG, Leverkusen, Germany represented by the Management Board: Werner Baumann, Chairman Bill Anderson, Sarena Lin, Wolfgang Nickl, Stefan Oelrich, Rodrigo Kaiser-Wilhelm-Allee 1 51373 Leverkusen, Germany Tel.: +49 (0)214 30-1 E-mail: Inquiries can be sent to info@bayer.com or using our contact form. Entry in the Commercial Register of the Cologne District Court (Amtsgericht): HRB 48248 Turnover tax ID no.: DE 123659859 Edited by: Bayer AG Communications & Public Affairs

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Publishing Since

2/22/2022

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Recent Episodes

April 3, 2023

XARENO 2 - Year Data - Expert Podcast With Manesh Patel And Peter Rossing

How do new insights from the XARENO study impact treatment options for patients with AF and advanced CKD? In this episode, Dr Manesh Patel and Dr Peter Rossing expand upon the XARENO 2-year outcomes data presented at the ACC 2023 congress. The experts provide cardiology and endocrinology perspectives into how these results add to the wealth of randomized clinical trial and real-world data to determine the treatment options for patients with AF and advanced CKD. The views and opinions expressed throughout this podcast are those of the speakers based on their expertise and do not necessarily reflect those of Bayer. The Bayer product rivaroxaban is discussed during this episode. Rivaroxaban is indicated for the prevention of stroke and systemic embolism in adult patients with non-valvular atrial fibrillation with one or more risk factors, such as congestive heart failure, hypertension, age ≥75 years, diabetes mellitus, prior stroke or transient ischaemic attack. Further details: • The ACC 2023 presentation of the 2-year XARENO data can be accessed here: https://www.abstractsonline.com/pp8/#!/10674/presentation/19112 • The 1-year results from the XARENO study can be found here https://www.ahajournals.org/doi/10.1161/circ.142.suppl_3.13927, here https://www.researchgate.net/profile/Kai-Hahn2/publication/360217368_ACC22_XARENO_Poster_Final/links/6268ee8e8e6d637bd101 b8d0/ACC22-XARENO-Poster-Final.pdf and here https://www.jacc.org/doi/abs/10.1016/S0735-1097%2822%2901192-5 • The XARENO study design is available here: https://journals.viamedica.pl/kardiologia_polska/article/view/86346 • Access the ROCKET AF manuscript here: https://www.nejm.org/doi/full/10.1056/nejmoa1009638 • The 2020 ESC guidelines for AF treatment can be accessed here: https://www.escardio.org/Guidelines/Clinical-Practice-Guidelines/Atrial-FibrillationManagement • AF treatment guidelines published by the AHA/ACC/AHS in 2019 can be found here: 230313-XARENO 2 year outcomes podcast shownotes-draft3 4 https://www.ahajournals.org/doi/10.1161/CIR.0000000000000665 • For anticoagulant dosing information, see the European labels for apixaban (http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_- _Product_Information/human/002148/WC500107728.pdf), dabigatran (http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_- _Product_Information/human/000829/WC500041059.pdf), edoxaban (http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_- _Product_Information/human/002629/WC500189045.pdf), rivaroxaban (https://www.ema.europa.eu/documents/product-information/xarelto-epar-productinformation_en.pdf) and warfarin (https://www.medicines.org.uk/emc/product/3064/smpc) MA-M_RIV-ALL-1368-2 & MA-M_RIV-ALL-1370-2

September 6, 2022

The beginning of the end for NOACs? The extra mile

This podcast is a follow-up to Bayer’s symposium at ESC 2022, ‘The beginning of the end for NOACs? The extra mile’. In this episode, Dr Manesh Patel and Professor Rupert Bauersachs expand on the discussions from the symposium, providing further insight into the management of frail patients with AF and VTE. The experts also provide their perspectives on the treatment of paediatric patients with VTE and patients with cancer-associated thrombosis, evaluating the available evidence to guide decision-making for these particularly vulnerable patients. The views and opinions expressed throughout this podcast are those of the speakers based on their expertise and do not necessarily reflect those of Bayer. Further details: • The EINSTEIN programme publications can be found here for EINSTEIN PE (https://www.nejm.org/doi/full/10.1056/NEJMoa1113572), EINSTEIN DVT (https://www.nejm.org/doi/full/10.1056/NEJMoa1007903), EINSTEIN Pooled (https://thrombosisjournal.biomedcentral.com/articles/10.1186/1477-9560-11-21), EINSTEIN CHOICE (https://www.nejm.org/doi/full/10.1056/nejmoa1700518) and EINSTEIN JUNIOR (https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(19)30219-4/fulltext) • Real-world evidence published by Craig Coleman on the efficacy and safety of rivaroxaban versus warfarin in frail patients with VTE can be accessed here: https://www.amjmed.com/article/S0002-9343(18)30202-X/fulltext • The XALIA study publication can be found here: https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(15)00257-4/fulltext • The findings from the XANTUS trial are available here: https://academic.oup.com/eurheartj/article/37/14/1145/2466063 • Access the ROCKET AF manuscript here: https://www.nejm.org/doi/full/10.1056/nejmoa1009638 • The elderly subgroup analysis of ROCKET AF can be found here: https://www.ahajournals.org/doi/10.1161/circulationaha.113.005008 • Findings from the SAFIR trial can be accessed here: https://heart.bmj.com/content/107/17/1376 • Find the edoxaban phase II trial paper here: https://www.thieme-connect.com/products/ejournals/abstract/10.1160/TH10-01-0066 • Read the SELECT-D study paper here: https://ascopubs.org/doi/10.1200/JCO.2018.78.8034 • Information on the OSCAR trials can be found here for the UK (https://clinicaltrials.gov/ct2/show/NCT05112666, https://abstracts.isth.org/abstract/comparison-of-effectiveness-and-safety-of-direct-oral-anticoagulant-versus-low-molecular-weight-heparin-treatment-for-venous-thromboembolism-in-patients-with-active-cancer-the-oscar-uk-study/) and the US (https://clinicaltrials.gov/ct2/show/NCT04979780, https://www.sciencedirect.com/science/article/pii/S0006497121040908) • Details on the Mayo Clinic prospective cohort study are available here: https://www.mayoclinicproceedings.org/article/S0025-6196(21)00435-3/fulltext • Support for the proportion of patients not receiving anticoagulation can be accessed here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278389/#CIT0011 • For anticoagulant dosing information, see the European labels for apixaban (http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/002148/WC500107728.pdf), dabigatran (http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/000829/WC500041059.pdf), edoxaban (http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/002629/WC500189045.pdf), rivaroxaban (https://www.ema.europa.eu/documents/product-information/xarelto-epar-product-information_en.pdf) and warfarin (https://www.medicines.org.uk/emc/product/3064/smpc) Audio: MA-M_RIV-ALL-1236-1 Shownotes: MA-M_RIV-ALL-1237-1

June 15, 2022

Extended anticoagulation in patients with VTE: The importance of patient preference

In this episode, Professor Jan Beyer-Westendorf and Professor Rupert Bauersachs discuss the latest real-world evidence for the extended treatment of patients with venous thromboembolism (VTE). They focus on data published from the all-comer Dresden NOAC Registry, which provides important insights on the adherence patterns of patients with VTE on anticoagulation treatment beyond 12 months. Our experts also discuss the FIRST and SWIVTER registries, and how their findings highlight the importance of patient preference in maintaining patient persistence with extended treatment in order for patients to gain the full benefits of their treatment. The views and opinions expressed throughout this podcast are those of the speakers based on their expertise and do not necessarily reflect those of Bayer. • You can read the most up to date CHEST guidelines here: https://journal.chestnet.org/article/S0012-3692(21)01507-5/fulltext • The Dresden NOAC Registry showed high persistence of patients with VTE on rivaroxaban, these results can be viewed here: https://www.thrombosisresearch.com/article/S0049-3848(21)00515-6/fulltext • EINSTEIN CHOICE investigated the extended treatment of VTE patients with rivaroxaban versus aspirin, results from the trial can be found here: https://www.nejm.org/doi/full/10.1056/nejmoa1700518 • The FIRST registry is the largest real-world evidence registry for rivaroxaban to date, read about its findings on treatment adherence here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606029/ • Read more about the insights from the SWIVTER registry here: https://www.thiemeconnect.com/products/ejournals/abstract/10.1160/TH16-03-0209 • The EINSTEIN EXTENSION study our experts discuss in this podcast can be found here: https://www.nejm.org/doi/full/10.1056/nejmoa1007903 Extended treatment VTE podcast-draft1 4 • The pooled results from the EINSTEIN PE and EINSTEIN DVT studies are available here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850944/ • For anticoagulant dosing information, see the European labels for apixaban (Eliquis) (http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_- _Product_Information/human/002148/WC500107728.pdf), dabigatran (Pradaxa) (http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_- _Product_Information/human/000829/WC500041059.pdf), edoxaban (Lixiana) (http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_- _Product_Information/human/002629/WC500189045.pdf), rivaroxaban (Xarelto) (https://www.ema.europa.eu/documents/product-information/xarelto-epar-productinformation_en.pdf) and warfarin (https://www.medicines.org.uk/emc/product/3064/smpc) Recording approval: PP-XAR-ALL-2638-1 Shownotes approval: PP-XAR-ALL-2639-1

8 total episodes available with 1 transcripts

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Frequently asked questions

Have a different question and can't find the answer you're looking for? Reach out to our support team by sending us an email and we'll get back to you as soon as we can.

What is Vascular Adviser Podcast?: The audio files provided on the Thrombosis Adviser channel are intended for viewers outside the USA and the UK only.

Thrombosis Adviser is an online resource for physicians and patients about current and emerging therapies for thromboembolic disease including venous thrombosis (VTE), atrial fibrillation (AF), and acute coronary syndrome (ACS). The Thrombosis Adviser podcast series is intended to provide information to HPCs.

Imprint

Published by: Bayer AG, Leverkusen, Germany represented by the Management Board: Werner Baumann, Chairman Bill Anderson, Sarena Lin, Wolfgang Nickl, Stefan Oelrich, Rodrigo

Kaiser-Wilhelm-Allee 1 51373 Leverkusen, Germany Tel.: +49 (0)214 30-1

E-mail: Inquiries can be sent to info@bayer.com or using our contact form. Entry in the Commercial Register of the Cologne District Court (Amtsgericht): HRB 48248 Turnover tax ID no.: DE 123659859

Edited by: Bayer AG Communications & Public Affairs
How often does this podcast release new episodes?: This podcast updates daily.
Where can I listen to this podcast?: This podcast is available on 4 platforms including Apple Podcasts, Spotify, and more. You can also use the RSS feed directly.
Does this podcast accept guests?: Yes, this podcast regularly features guests.

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