Podcast thumbnail for Blood Cancer Talks

Blood Cancer Talks

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by Rajshekhar Chakraborty, Ashwin Kishtagari, and Edward Cliff

4.8(86 reviews)
72 episodes
Updated Bi-weekly
Accepts GuestsHas SponsorsLocation 🇺🇸
37

Podcast Authority

Beta
PoorBased on show quality, social media presence, reviews, charts, and more
Pod Engine
Quality9
Social0
YouTube76
Engagement85

Podcast Overview

This is a podcast on latest advances in the understanding and management of blood cancers. Here, we will bring a wide range of experts within hematologic malignancies to discuss various topics in depth. Host: Raj Chakraborty, MD from Columbia University, New York, Ashwin Kishtagari, MD, from Vanderbilt University, Nashville, and Edward Cliff, MD, from Harvard University, Boston Tweet your suggestions and feedback to @rajshekharucms @AshKishtagari @Eddie_Cliff @BloodCancerTalk

Language

🇺🇲

Publishing Since

7/8/2022

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37

Podcast Authority

Beta
PoorBased on show quality, social media presence, reviews, charts, and more
Pod Engine
Quality9
Social0
YouTube76
Engagement85
5
Excellent Areas
2
Good Performance
12
Growth Opportunities
excellent
Episode Length
46 minutes
Performing excellently!
good
Show Notes Quality
3.0/5

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Every 18 days

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Recent Episodes

Episode thumbnail for Episode 71. Management of Newly Diagnosed Multiple Myeloma with Dr. Vincent Rajkumar

May 19, 2026

Episode 71. Management of Newly Diagnosed Multiple Myeloma with Dr. Vincent Rajkumar

Host Ashwin Raj and Eddie interview Dr. Vincent Rajkumar, Mayo Clinic Professor, discussing newly diagnosed multiple myeloma management, from workup to maintenance strategies.

Episode thumbnail for Episode 70. ASH 2025 Myeloid Neoplasm Roundup with Dr. Curtis Lachowiez

February 27, 2026

Episode 70. ASH 2025 Myeloid Neoplasm Roundup with Dr. Curtis Lachowiez

<p><br>In this episode, we dive deep into ASH 2025 updates on myeloid malignancies with Dr. Curtis Lachowiez. From the plenary halls of ASH 2025 to long-term follow-up of Aza/Ven/Gilteritinib, we unpack what the latest evidence means for the future of AML management.<br><strong><br>1. PARADIGM Trial (Plenary Session, Abstract 6)</strong></p><p>Fathi A, Perl A, Fell G, et al. Results from PARADIGM – a phase 2 randomized multi-center study comparing azacitidine and venetoclax to conventional induction chemotherapy for newly diagnosed fit adults with acute myeloid leukemia. Blood 2025;146(Suppl 1):6.</p><p><a href="https://doi.org/10.1182/blood-2025-6">https://doi.org/10.1182/blood-2025-6</a></p><p>ClinicalTrials.gov: <a href="https://clinicaltrials.gov/ct2/show/NCT04801797">NCT04801797</a></p><p><strong><br>2. VICEROY Study – Aza/Ven/Gilteritinib Triplet (Abstract 654)</strong></p><p>Venetoclax (VEN) and azacitidine (AZA) with gilteritinib (GILT) in patients with newly diagnosed FLT3mut+ AML ineligible for intensive induction chemotherapy: Interim results from the phase 1/2 VICEROY study. Blood 2025;146(Suppl 1):654.</p><p>ClinicalTrials.gov: <a href="https://clinicaltrials.gov/ct2/show/NCT05520567">NCT05520567</a></p><p><strong><br>3. Long-Term Follow-Up of Aza/Ven/Gilteritinib in FLT3-Mutated AML (Abstract 45)</strong></p><p>Azevedo RS, et al. Long-term follow-up of azacitidine, venetoclax, and gilteritinib in patients with newly diagnosed FLT3-mutated acute myeloid leukemia. Blood 2025;146(Suppl 1):45.</p><p>Original publication: Short NJ, Daver N, DiNardo CD, et al. J Clin Oncol 2024;42:1499–1508. <a href="https://doi.org/10.1200/JCO.23.01911">https://doi.org/10.1200/JCO.23.01911</a></p><p>ClinicalTrials.gov: <a href="https://clinicaltrials.gov/ct2/show/NCT04140487">NCT04140487</a></p><p><strong><br>4. PRISM-AML Score (Abstract 453)</strong></p><p>Lachowiez CA, et al. Prognostic risk integration for survival modeling (PRISM) in newly diagnosed acute myeloid leukemia treated with venetoclax: A multinational retrospective cohort study. Blood 2025;146(Suppl 1):453.</p><p>Interactive Calculator: <a href="https://prism-aml.com">https://prism-aml.com</a></p><p><strong><br>5. Additional Studies Referenced in Discussion</strong></p><p>•       <strong>VIALE-A Trial: </strong>DiNardo CD, et al. Azacitidine and venetoclax in previously untreated acute myeloid leukemia. N Engl J Med 2020;383:617–629. (NCT02993523)</p><p>•       <strong>VERONA Trial: </strong>Randomized study of Aza-Ven vs. Aza vs. placebo in MDS (discussed as a negative study)</p><p>•       <strong>4-Gene Classifier (mPRS): </strong>Bataller A, et al. Prognostic risk signature in patients with AML treated with HMA and venetoclax. Blood Adv 2024;8(4):927–935. <a href="https://doi.org/10.1182/bloodadvances.2023011757">https://doi.org/10.1182/bloodadvances.2023011757</a></p><p>•       <strong>LACEWING Trial: </strong>Azacitidine plus gilteritinib vs. azacitidine plus placebo in FLT3-mutated AML (discussed as a negative study)</p><p> </p>

Episode thumbnail for Episode 69. ASH 2025 Lymphoma Roundup with Dr. Carla Casulo

January 22, 2026

Episode 69. ASH 2025 Lymphoma Roundup with Dr. Carla Casulo

<p>BloodCancerTalks: ASH 2025 Lymphoma Roundup</p><p>Guest: Dr. Carla Casulo, Associate Professor, Wilmot Cancer Centre, University of Rochester</p><p><strong>Abstracts Discussed</strong></p><p><strong>Follicular Lymphoma</strong></p><p>EPCORE-FL1 (Falchi) - Epcoritamab plus lenalidomide-rituximab (R2) in relapsed/refractory FL</p><p>Theme: Bispecific antibody combinations in R/R FL; comparing to other approaches</p><p> </p><p><strong>Diffuse Large B-Cell Lymphoma (DLBCL) - Elderly/Unfit Patients</strong></p><p>MorningSun (Sharman) - Mosunetuzumab monotherapy in patients ≥80 years or chemo-ineligible</p><p>EPCOR-DLBCL-3 (Vitolo) - Epcoritamab monotherapy in elderly patients</p><p>R-Pola-Glo - Rituximab-polatuzumab-glofitamab combination in older/frail patients</p><p>Theme: Single-agent and combination bispecific strategies for elderly and frail DLBCL patients</p><p> </p><p><strong>DLBCL - First-Line Treatment</strong></p><p>SMART STOP (Westin) - Chemotherapy-free approach using lenalidomide, tafasitamab, rituximab, acalabrutinib (ULTRA regimen)</p><p>FrontMIND - Tafasitamab-lenalidomide added to R-CHOP</p><p>Theme: Chemotherapy-sparing and chemo-intensification strategies in newly diagnosed DLBCL</p><p> </p><p><strong>DLBCL - Relapsed/Refractory</strong></p><p>DALY 2-EU (Borchmann) - Dual CD19/CD20 CAR-T (zamto-cel) versus R-GemOx in transplant-ineligible patients</p><p>Theme: Expanding CAR-T eligibility; treatment selection in transplant-ineligible R/R DLBCL</p><p> </p><p><strong>Hodgkin Lymphoma</strong></p><p>SWOG 1826 - 3-year update: Nivolumab-AVD versus brentuximab-AVD</p><p>HD21 - 5-year update: PET-adapted BrECADD versus BEACOPP</p><p>Theme: Long-term outcomes and treatment selection in newly diagnosed Hodgkin lymphoma</p><p><strong> </strong></p><p><strong>Burkitt Lymphoma</strong></p><p>ZUMA-25 (Van Dorp) - Brexucabtagene autoleucel (Brexu-cel) in relapsed/refractory Burkitt</p><p>Theme: CAR-T therapy for the challenging population of R/R Burkitt lymphoma</p><p> </p><p><strong>Mantle Cell Lymphoma - First-Line</strong></p><p> </p><p>TrAVeRse - Acalabrutinib, venetoclax, rituximab</p><p>GLOVe - Glofitamab, lenalidomide, venetoclax (high-risk MCL)</p><p>BOVen - Zanubrutinib, obinutuzumab, venetoclax (older patients)</p><p>MAVO - Acalabrutinib, venetoclax, obinutuzumab</p><p>Window-3 - Acalabrutinib-rituximab followed by brexu-cel (high-risk MCL)</p><p>Theme: Chemotherapy-free combinations in newly diagnosed mantle cell lymphoma</p>

72 total episodes available with 1 transcripts

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Frequently asked questions

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What is Blood Cancer Talks?

This is a podcast on latest advances in the understanding and management of blood cancers. Here, we will bring a wide range of experts within hematologic malignancies to discuss various topics in depth. Host: Raj Chakraborty, MD from Columbia University, New York, Ashwin Kishtagari, MD, from Vanderbilt University, Nashville, and Edward Cliff, MD, from Harvard University, Boston Tweet your suggestions and feedback to @rajshekharucms @AshKishtagari @Eddie_Cliff @BloodCancerTalk

How often does this podcast release new episodes?

This podcast updates bi-weekly.

Where can I listen to this podcast?

This podcast is available on 10 platforms including Apple Podcasts, Spotify, and more. You can also use the RSS feed directly.

Does this podcast accept guests?

No, this podcast does not typically feature guests.

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