Endocrine Feedback Loop is a monthly journal club podcast series brought to you by the Endocrine Society. Hosted by endocrinologist Chase Hendrickson, MD, from Vanderbilt University, each episode features an expert educator and a topical specialist dissecting recently published journal articles and discussing implications for clinical practice.
Endocrine Feedback Loop
Claim This Podcastby Endocrine Society
5.0(20 reviews)
77 episodes
Updated Bi-weekly
Accepts GuestsHas SponsorsLocation 🇺🇸
58
Podcast Authority
BetaFairBased on show quality, social media presence, reviews, charts, and more
Quality49
Social0
YouTube86
Engagement82
Podcast Overview
Endocrine Feedback Loop is a monthly journal club podcast series brought to you by the Endocrine Society. Hosted by endocrinologist Chase Hendrickson, MD, from Vanderbilt University, each episode features an expert educator and a topical specialist dissecting recently published journal articles and discussing implications for clinical practice.
Language
🇺🇲
Publishing Since
5/20/2020
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58
Podcast Authority
BetaFairBased on show quality, social media presence, reviews, charts, and more
Quality49
Social0
YouTube86
Engagement82
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Episode Length
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Recent Episodes
July 16, 2026
EFL075 - Methimazole Titration and Initial Disease Severity in Graves' Disease
<p>How does the severity of Graves disease at presentation affect subsequent methimazole dose titration? Find out more in this month's episode!</p><p>For our 75th episode, we review a forthcoming Journal of Clinical Endocrinology & Metabolism study examining whether the severity of Graves disease at presentation influences methimazole titration and treatment management. Drawing on a retrospective longitudinal cohort of 152 patients, the study provides a real-world look at antithyroid drug dosing and monitoring practices.</p><p>Host Chase Hendrickson, MD, MPH, MMHC, from Vanderbilt University, is joined by new regular contributor Jonea Lim, MD, from the University of Oklahoma, and guest expert Elizabeth Pearce, MD, MSc, from Boston University. Together, they discuss <a target="_blank" rel="noopener noreferrer nofollow" href="https://doi.org/10.1210/clinem/dgag134">“Initial disease severity and methimazole titration for Graves' disease: a retrospective longitudinal cohort study”</a> and explore its implications for the clinical management of Graves disease.</p><p>Want to learn more? Visit the<a target="_blank" rel="noopener noreferrer nofollow" href="https://www.endocrine.org/journals/endocrine-feedback-loop-podcast-series/efl075"> </a><a target="_blank" rel="noopener noreferrer" class="fui-Link fai-bebop ___1v1lyro f2hkw1w f3rmtva f1ewtqcl f16muhyy f1k6fduh f1w7gpdv f1mo0ibp fjoy568 ff5ikls f1s184ao f1mk8lai fnbmjn9 f1o700av f13mvf36 f33ey8m f9n3di6 f1ids18y f1tx3yz7 feiuef2 f1eh06m1 f54796x fhgqx19 f1olyrje f1p93eir f1nev41a f132whgj f1v74mp6 f1tsf1ni fnq52rx f16zlvvm" href="https://www.endocrine.org/journals/endocrine-feedback-loop-podcast-series/efl075">Episode 75 webpage</a> for additional resources and information about our guests and host.</p>
June 18, 2026
EFL074 - Taking Levothyroxine Fasting vs. With Breakfast
<p>For our 74th episode, recorded live at ENDO 2026 in Chicago, we review a recent JCEM study that addresses a common clinical question: does levothyroxine need to be taken on an empty stomach?</p><p>This randomized clinical trial evaluates a dose-adjusted, non-fasting regimen and finds that a 15% increase with breakfast ingestion achieves TSH stability similar to that with standard fasting dosing. The results also suggest potential improvements in adherence and patient-reported well-being, while highlighting variability in dose adjustments and limitations in generalizability.</p><p>Host Chase Hendrickson, MD, MPH, MHCC, from Vanderbilt University, is joined by regular contributor Andy Crawford, MD, from Dartmouth-Hitchcock Medical Center, and guest expert Matt Edelson, MD, from the University of Chicago. Together, they discuss <a target="_blank" rel="noopener noreferrer nofollow" href="https://doi.org/10.1210/clinem/dgaf686">“Fasting versus non-fasting dose-adjusted levothyroxine ingestion in hypothyroidism,”</a> published in the April 2026 issue of JCEM, and consider how these findings may inform patient-centered approaches to medication timing and management.</p>
May 21, 2026
EFL073 - Infrequent Zoledronate in Low Fracture Risk
<p>For our 73rd episode and the start of the seventh season, we review a recent study examining the long-term anti-fracture efficacy of infrequent zoledronate dosing in women with osteopenia. While current clinical approaches typically focus on treating individuals at higher fracture risk, this study explores whether earlier intervention in lower-risk populations may help reduce fracture risk over time.</p><p>This secondary analysis of a randomized clinical trial evaluates the effects of zoledronate administered at extended intervals, with outcomes assessed over a 10-year period. The findings suggest that infrequent dosing may be associated with meaningful reductions in vertebral, major osteoporotic, and overall fracture risk, particularly in the later years of follow-up. The study also examines how fracture risk relates to baseline risk factors and changes in bone mineral density, raising questions about the role of routine monitoring and the timing of preventive therapy.</p><p>Host Chase Hendrickson, MD, MPH, MHCC, from Vanderbilt University, talks with regular contributor Amal Shibli Rahhal, MD, from the University of Iowa, and guest expert Thomas Weber, MD, from Duke Health. Together, they discuss <a target="_blank" rel="noopener noreferrer nofollow" href="https://doi.org/10.1210/clinem/dgaf569"><strong>“Anti-fracture efficacy of 5 or 10 yearly zoledronate in women aged 50 to 60 years,”</strong></a> published in the April 2026 issue of JCEM, and consider how these findings may inform decisions around early treatment strategies, risk assessment, and long-term fracture prevention in clinical practice.</p>
77 total episodes available
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This podcast updates bi-weekly.
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