Learn more about gout causes, symptoms, and treatment with Gout Education Society Chairman, Larry Edwards, MD, MACR, MACP, alongside other gout experts from across the world.
Welcome to the second season finale Kicking Gout in the Acid. This season dove into additional topics of importance to not only those with gout, but for those treating the disease as well. Whether you’ve been recently diagnosed, care for someone suffering, or are a medical professional treating the disease, the Kicking Gout in the Acid podcast can help you learn more.
The season finale of Kicking Gout in the Acid features a conversation between Dr. Larry Edwards and Dr. Brian Mandell, rheumatologist from the Cleveland Clinic, and member of the Gout Education Society’s Board of Directors. In this episode, Dr. Edwards and Dr. Mandell will look back at the history of gout treatment, discuss the current state of affairs for medications in development, and look towards the future of disease management.
Key Takeaways:
Early treatments focused on symptom relief rather than the underlying disease, delaying recognition of gout as a condition driven by urate deposition that requires targeted, long‑term management.
Medications like probenecid and later allopurinol reframed gout as a chronic condition that can be controlled by consistently lowering and maintaining serum urate to a defined target. This strategy opened the door to new options like febuxostat, uricosurics, and uricase-based therapies that allow for more individualized care.
The future of gout treatment is bright with options as many are in the clinical pipeline. To Dr. Edwards and Dr. Mandell, an option that not only lowers urate more effectively but also directly targets inflammation pathways could be an interesting area of future research.
Gout is treatable and curable when managed correctly. Successful outcomes depend on a team-based approach involving informed patients, appropriate medication use, adherence to treat‑to‑target principles, and consistent follow‑up.
Start your journey with gout today via the Gout Education Society website and sign up for the monthly newsletter.
Follow the Gout Education Society on X and Facebook
Looking for nearby gout specialists? Find rheumatologists, nephrologists and more via the Gout Specialists Network.
Educational Materials:
Gout Patient Brochure
Medical Professional Guide
Crystal Clear Checklist
Kicking Gout in the Acid is sponsored by Sobi.
31 Mar 2026
Heart Health and Gout: Connecting the Dots
Welcome to season two of Kicking Gout in the Acid. This season will dive into additional topics of importance to not only those with gout, but for those treating the disease as well. Whether you’ve been recently diagnosed, care for someone suffering, or are a medical professional treating the disease, the Kicking Gout in the Acid podcast can help you learn more.
This episode of Kicking Gout in the Acid features a conversation between Dr. Larry Edwards and Dr. Ken Saag, rheumatologist, professor, and director in UAB Medicine’s Division of Clinical Immunology and Rheumatology, member of the Gout Education Society’s Board of Directors. The two dive into the link between gout and cardiovascular disease, why flares may increase risk for CV events, and clinical recommendations that medical professionals should consider when someone faces both conditions.
Key Takeaways:
The link between gout and cardiovascular disease remains complex and often misunderstood. While biological plausibility exists, human data are mixed, creating uncertainty about how strongly uric acid contributes to long‑term heart outcomes.
Gout flares themselves may carry cardiovascular risk. Acute flares are highly inflammatory, and emerging evidence suggests they may directly increase the likelihood of cardiovascular events which underscores the need for proactive flare prevention.
Those with both gout and heart disease benefit from aggressive management based on the treat-to-target approach. Lowering serum urate, preventing flares, and maintaining overall cardiovascular stability remain key goals for improving outcomes for those facing both conditions.
Lifestyle changes can be helpful in those with gout, but medication is essential to treat a majority of cases. Although weight loss and dietary changes provide modest improvements, they rarely reduce uric acid enough on their own. Sustainable management still depends on appropriately titrated urate‑lowering therapy.
Start your journey with gout today via the Gout Education Society website and sign up for the monthly newsletter.
Follow the Gout Education Society on X and Facebook
Looking for nearby gout specialists? Find rheumatologists, nephrologists and more via the Gout Specialists Network.
Educational Materials:
Gout Patient Brochure
Medical Professional Guide
Crystal Clear Checklist
Kicking Gout in the Acid is sponsored by Sobi.
23 Feb 2026
The Challenge of Coordinated Gout Treatment
Welcome to season two of Kicking Gout in the Acid. This season will dive into additional topics of importance to not only those with gout, but for those treating the disease as well. Whether you’ve been recently diagnosed, care for someone suffering, or are a medical professional treating the disease, the Kicking Gout in the Acid podcast can help you learn more.
This episode of Kicking Gout in the Acid features a conversation between Dr. Larry Edwards and Dr. Tuhina Neogi, Professor of Medicine at Boston University Chobanian & Avedisian School of Medicine (BUSM), Chief of Rheumatology at Boston Medical Center, and member of the Gout Education Society’s Board of Directors. The two explore the common areas where gout patients are seen, common pitfalls that occur throughout the process of multidisciplinary management, and the importance of promoting the ACR gout guidelines among professionals.
Key Takeaways:
Gout is still not viewed as an important rheumatic disease by many providers, leading to under-treatment and missed opportunities for proper management. Under-treated gout, or treatment only focused on symptoms, can lead to uncontrolled hyperuricemia, worsening tophi, and patients losing trust in their physicians.
There is growing involvement in specialists treating gout, however, inconsistent knowledge on managing the disease can lead to unnecessary medication holds, recurrent flares, and patient confusion.
Many myths still hold the attention of those with the disease and medical professionals alike. Notably, the disease shouldn’t be seen as episodic, rather it should be seen as chronic, requiring lifelong therapy that aligns with the treat-to-target approach.
Educated patients are advocates for themselves. This can be particularly helpful when their care team has differing opinions.
Start your journey with gout today via the Gout Education Society website and sign up for the monthly newsletter.
Follow the Gout Education Society on X and Facebook
Looking for nearby gout specialists? Find rheumatologists, nephrologists and more via the Gout Specialists Network.
Educational Materials:
Gout Patient Brochure
Medical Professional Guide
Crystal Clear Checklist
Kicking Gout in the Acid is sponsored by Sobi.
30 Jan 2026
Gout and Genetics: What Your Background Might Mean
Welcome to season two of Kicking Gout in the Acid. This season will dive into additional topics of importance to not only those with gout, but for those treating the disease as well. Whether you’ve been recently diagnosed, care for someone suffering, or are a medical professional treating the disease, the Kicking Gout in the Acid podcast can help you learn more.
This episode of Kicking Gout in the Acid features a conversation between Dr. Larry Edwards and Dr. Robert Keenan, Rheumatologist, Chief Medical Officer at Arthrosi Therapeutics, and member of the International Advisory Council for the Gout Education Society. The two explore the broad reach of gout across different demographics, discuss how gout presents differently, and considerations healthcare professionals should be aware of during treatment.
Key Takeaways:
Gout doesn’t discriminate by age, gender, background, or diet. Doctors should be aware that the signs of gout aren’t always as straightforward. Misdiagnosis is common, so it’s important to take a step back and recognize the subtle symptoms.
Genetics play a meaningful, but complex, role. Family history is a significant risk factor, however, research points to polygenic and epigenetic factors than one single genetic mutation.
Demographics matter, but not in the way most people think. While men typically develop gout in their 40s-50s, the prevalence is nearly equal in women post-menopause.
Start your journey with gout today via the Gout Education Society website and sign up for the monthly newsletter.
Follow the Gout Education Society on X and Facebook
Looking for nearby gout specialists? Find rheumatologists, nephrologists and more via the Gout Specialists Network.
Educational Materials:
Gout Patient Brochure
Medical Professional Guide
Crystal Clear Checklist
Kicking Gout in the Acid is sponsored by Sobi.
10 Dec 2025
The Two-Way Street: Gout’s Impact on Renal Function – and Vice Versa
Welcome to season two of Kicking Gout in the Acid. This season will dive into additional topics of importance to not only those with gout, but for those treating the disease as well. Whether you’ve been recently diagnosed, care for someone suffering, or are a medical professional treating the disease, the Kicking Gout in the Acid podcast can help you learn more.
This episode of Kicking Gout in the Acid features a conversation between Dr. Larry Edwards and Dr. Richard Johnson, board-certified nephrologist and member of the Board of Directors for the Gout Education Society. The two explore the connection between gout and kidney health through topics like uric acid regulation through the kidneys, treatment options, and considerations for medical professionals in charge of care should keep in mind.
Key Takeaways:
The kidneys play a central role in uric acid regulation. About two-thirds of uric acid is excreted by the kidneys, and one-third by the gut. When kidney function declines, uric acid retention occurs, increasing gout risk.
Kidney disease and gout are closely linked to one another. Chronic kidney disease (CKD) is a major cause of gout because impaired kidney function leads to uric acid buildup. Conversely, high uric acid may contribute to CKD progression, creating a vicious cycle.
In those with kidney disease, treatment can look a bit different. Notably, NSAIDs may not be an option due to their harmful impact on the kidneys. For those with kidney disease looking for pain relief from a gout flare, options like steroids should be considered. Also, historical dosing restrictions for allopurinol in CKD have led to undertreatment, but recent evidence supports gradual titration to higher doses when monitored.
For medical professionals, it’s important to screen those with gout for kidney disease and vice versa. Medications known to raise uric acid should also be reviewed, namely, diuretics. Comorbidities should always be considered when treating gout.
Start your journey with gout today via the Gout Education Society website and sign up for the monthly newsletter.
Follow the Gout Education Society on X and Facebook
Looking for nearby gout specialists? Find rheumatologists, nephrologists and more via the Gout Specialists Network.
Educational Materials:
Gout Patient Brochure
Medical Professional Guide
Crystal Clear Checklist
Kicking Gout in the Acid is sponsored by Sobi.
30 Oct 2025
Living with Gout: Breaking the Silence on Stigma and Struggle
Welcome to season two of Kicking Gout in the Acid. This season will dive into additional topics of importance to not only those with gout, but for those treating the disease as well. Whether you’ve been recently diagnosed, care for someone suffering, or are a medical professional treating the disease, the Kicking Gout in the Acid podcast can help you learn more.
This episode of Kicking Gout in the Acid features a conversation between Dr. Larry Edwards and Gary Ho, Executive Director and Co-Founder, Gout Support Group of America. The two explore the connection between gout and mental health, highlighting the emotional toll of the disease, the stigma patients face, and the importance of correcting misconceptions. The episode features a candid conversation with a gout patient and offers insights for both patients and healthcare professionals on improving care and understanding
Key Takeaways:
The impact of gout goes beyond physical symptoms. Chronic pain, frequent flares and physical limitations also lead to mental anguish, which can be compounded through feeling unheard or dismissed by healthcare providers.
The stigma surrounding gout is often tied to outdated beliefs about diet and overindulgence. Many physicians also hold biases. Despite clear evidence that gout is a genetic disease, the stigma surrounding the disease leads to shame and guilt in those with the disease.
Misdiagnoses or dismissals of symptoms can occur, so it’s important for patients to monitor their flares and medical professionals to take patient-reported symptoms seriously.
Don’t give up—find your voice, seek support, and advocate for your health. There are resources for those dealing with the disease. Find support through the Gout Support Group of America, the Gout Education Society and other organizations.
Start your journey with gout today via the Gout Education Society website and sign up for the monthly newsletter.
Follow the Gout Education Society on X and Facebook
Looking for nearby gout specialists? Find rheumatologists, nephrologists and more via the Gout Specialists Network.
Educational Materials:
Gout Patient Brochure
Medical Professional Guide
Crystal Clear Checklist
Kicking Gout in the Acid is sponsored by Sobi.
30 May 2025
When Gout Becomes Hard to Manage – What to Expect
Dr. Herbert Baraf, an advisor at the National Institute of Health, joins Dr. Larry Edwards to examine the progression and management of gout, emphasizing early intervention to prevent advanced stages in this interview.
27 May 2025
Navigating Myths About Gout, and the Misconceptions and Stigma to Improve Management
Dr. Paul Doghramji discusses common misconceptions about gout's prevalence, causes, and treatments with Dr. Larry Edwards, emphasizing the need for education to dispel myths and improve patient care in this interview.
20 May 2025
The Severity Of Gout and the Importance of Gout Flare Management
Rheumatologists Dr. Larry Edwards and Dr. Brian Mandell discuss gout's root causes, diagnosis, and chronic management, emphasizing education's impact on improving gout flare management in this interview episode.
18 Feb 2025
The Gout Treatment Journey: Insights from a patient
Gout advocate Gary Ho shares his 30-year experience living with gout with Dr. Larry Edwards, highlighting self-advocacy and proactive care to manage uric acid levels, in this interview episode.
24 Jan 2025
Managing Gout Alongside Related Health Conditions
Rheumatologists Dr. Larry Edwards interviews Dr. Puja Khanna about managing gout with comorbidities like kidney disease and diabetes, highlighting the need for tailored treatment plans and proactive monitoring.
30 Dec 2024
The Socioeconomic Impact of Gout and Barriers to Treatment
Rheumatologist Dr. Jasvinder Singh discusses gout's socioeconomic impact and treatment barriers with Dr. Larry Edwards, highlighting the need for early management to reduce the economic burden on patients in this interview.
Who has been a guest on Kicking Gout in the Acid
Names identified in recent episode analyses. Showing up to five guests.
Dr Herbert Baraf
Dr Brian Mandell
Gary Ho
Dr Puja Khanna
Dr Jasvinder Singh
Reach and audience
Public platform figures. Ratings count people who left a rating, not total listeners.
YouTube views
141,261
Score snapshot 15 Sept 2025
Apple Podcasts (US)
5.0 / 5
4 ratings
Podcast Authority Score: 34 / 100
A composite of feed quality, social presence, YouTube performance and engagement. Read the methodology.
Quality
34
Social presence
0
YouTube
82
Engagement
0
Contact Kicking Gout in the Acid
Guest appearances
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