NETWise, a podcast about neuroendocrine cancer, is here to help patients and caregivers navigate the world of NETs.

NETWise
Claim This Podcastby Neuroendocrine Tumor Research Foundation (NETRF)
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NETWise, a podcast about neuroendocrine cancer, is here to help patients and caregivers navigate the world of NETs.
Language
🇺🇲
Publishing Since
8/5/2019
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Recent Episodes

June 19, 2026
EP 55: Do Zebras Change Their Stripes?
NETWise hosts interview Dr. Aman Chauhan, Dr. Nancy Joseph, Dr. Mark Lewis, and Dr. Jaydira Del Rivero about evolving neuroendocrine cancer biology and treatment adaptation.

May 1, 2026
Episode 54: Sitting With Uncertainty
Host Jessica Thomas interviews patients and Dr. Mark Lewis about navigating the profound uncertainty of a neuroendocrine cancer diagnosis and journey.

March 30, 2026
Episode 53: Understanding Pathology
<div data-elementor-type="wp-post" data-elementor-id="45286" class="elementor elementor-45286" data-elementor-post-type="podcast"> <div class="elementor-element elementor-element-51fd96cb e-flex e-con-boxed e-con e-parent" data-id="51fd96cb" data-element_type="container" data-e-type="container"> <div class="e-con-inner"> <div class="elementor-element elementor-element-4829489e elementor-widget elementor-widget-image" data-id="4829489e" data-element_type="widget" data-e-type="widget" data-widget_type="image.default"> <div class="elementor-widget-container"> <img fetchpriority="high" decoding="async" width="1024" height="576" src="https://netrf.org/wp-content/uploads/2026/03/EP-53-Understanding-Pathology_Horizontal-1024x576.png" class="attachment-large size-large wp-image-45289" alt="" srcset="https://netrf.org/wp-content/uploads/2026/03/EP-53-Understanding-Pathology_Horizontal-1024x576.png 1024w, https://netrf.org/wp-content/uploads/2026/03/EP-53-Understanding-Pathology_Horizontal-300x169.png 300w, https://netrf.org/wp-content/uploads/2026/03/EP-53-Understanding-Pathology_Horizontal-768x432.png 768w, https://netrf.org/wp-content/uploads/2026/03/EP-53-Understanding-Pathology_Horizontal-1536x864.png 1536w, https://netrf.org/wp-content/uploads/2026/03/EP-53-Understanding-Pathology_Horizontal.png 1920w" sizes="(max-width: 1024px) 100vw, 1024px" /> </div> </div> </div> </div> <div class="elementor-element elementor-element-5e9d6b25 e-flex e-con-boxed e-con e-parent" data-id="5e9d6b25" data-element_type="container" data-e-type="container"> <div class="e-con-inner"> <div class="elementor-element elementor-element-3b75485b elementor-widget elementor-widget-text-editor" data-id="3b75485b" data-element_type="widget" data-e-type="widget" data-widget_type="text-editor.default"> <div class="elementor-widget-container"> <p>When someone is diagnosed with cancer, one of the first questions is simple — what exactly is it? The answer begins with better understanding pathology.</p><p>In this episode of NETWise, we examine the central role pathology plays in the diagnosis and management of neuroendocrine cancers — from initial biopsy through classification, grading, and treatment decision-making. Drawing on insights from leading clinicians, pathologists, and researchers, this conversation provides a clear, structured look at how diagnostic precision is established and why it is essential.</p><p>A biopsy — analyzed through pathology — is the gold standard for confirming a cancer diagnosis. By examining tumor tissue, pathologists determine not only whether cancer is present, but also define tumor type, differentiation, grade, and key biomarkers that directly inform prognosis and therapeutic strategy.</p><p>In neuroendocrine neoplasms, this level of detail is particularly critical. These diseases represent a heterogeneous spectrum, where tumors that may appear similar under the microscope can behave very differently clinically. Distinguishing between well-differentiated neuroendocrine tumors (NETs) and poorly differentiated neuroendocrine carcinomas (NECs), as well as accurately assessing measures of tumor growth, can significantly alter treatment pathways and outcomes.</p><p>This episode focuses on how those distinctions are made — and why they matter. It explores how pathology moves from a small tissue sample to a precise diagnosis, why interpretation can be complex, and why expert review is often essential, particularly in rare and high-grade disease.</p><p>We also address the real-world challenges of pathology interpretation in neuroendocrine cancer, including diagnostic complexity, evolving classification systems, and the importance of second opinions and specialized care.</p><p>For patients and caregivers, understanding pathology can help turn a confusing report into meaningful, actionable information. It can clarify what a diagnosis means, why specific treatments are recommended, and when it may be important to seek additional expertise.<br />It can also help patients ask better questions — about tumor type, grade, and next steps — and better understand the reasoning behind clinical decisions.</p><p>And behind every pathology report is a team of specialists looking closely and intentionally at the evidence — working to understand the biology of the disease as clearly as possible so that the next steps are as informed as possible.</p><p>Because understanding pathology isn’t just about learning the science.</p><p>It’s about turning confusion into clarity.<br />It’s about knowing what questions to ask.<br />And it’s about feeling more informed, more prepared, and more empowered in the moments that matter most.</p><p>This episode is designed to help bring that clarity — to better understand and demystify pathology, and to make the information behind a diagnosis more accessible, so patients and families can move forward with greater confidence.</p> </div> </div> </div> </div> <section class="elementor-section elementor-top-section elementor-element elementor-element-2e263fc3 elementor-section-boxed elementor-section-height-default elementor-section-height-default" data-id="2e263fc3" data-element_type="section" data-e-type="section"> <div class="elementor-container elementor-column-gap-default"> <div class="elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-2bd1a903" data-id="2bd1a903" data-element_type="column" data-e-type="column"> <div class="elementor-widget-wrap elementor-element-populated"> <div class="elementor-element elementor-element-1bf751f2 elementor-widget elementor-widget-text-editor" data-id="1bf751f2" data-element_type="widget" data-e-type="widget" data-widget_type="text-editor.default"> <div class="elementor-widget-container"> <h2><span style="font-size: 2rem;">NET specialists included in this episode</span></h2><h4 style="display: none;">Use our episode infographics to get a visual picture of some of the things we have discussed.</h4> </div> </div> <section class="elementor-section elementor-inner-section elementor-element elementor-element-23bfa84c elementor-section-boxed elementor-section-height-default elementor-section-height-default" data-id="23bfa84c" data-element_type="section" data-e-type="section"> <div class="elementor-container elementor-column-gap-default"> <div class="elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-3a87db0d" data-id="3a87db0d" data-element_type="column" data-e-type="column"> <div class="elementor-widget-wrap elementor-element-populated"> <div class="elementor-element elementor-element-22e395c4 elementor-widget elementor-widget-image" data-id="22e395c4" data-element_type="widget" data-e-type="widget" data-widget_type="image.default"> <div class="elementor-widget-container"> <img decoding="async" width="913" height="1024" src="https://netrf.org/wp-content/uploads/2025/12/Neil-Renwick--913x1024.png" class="attachment-large size-large wp-image-44341" alt="" srcset="https://netrf.org/wp-content/uploads/2025/12/Neil-Renwick--913x1024.png 913w, https://netrf.org/wp-content/uploads/2025/12/Neil-Renwick--268x300.png 268w, https://netrf.org/wp-content/uploads/2025/12/Neil-Renwick--768x861.png 768w, https://netrf.org/wp-content/uploads/2025/12/Neil-Renwick-.png 1138w" sizes="(max-width: 913px) 100vw, 913px" /> </div> </div> </div> </div> <div class="elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-4a65c80" data-id="4a65c80" data-element_type="column" data-e-type="column"> <div class="elementor-widget-wrap elementor-element-populated"> <div class="elementor-element elementor-element-60391423 elementor-widget elementor-widget-text-editor" data-id="60391423" data-element_type="widget" data-e-type="widget" data-widget_type="text-editor.default"> <div class="elementor-widget-container"> <p><strong>Neil Renwick, MD, PhD, FRCPC</strong><br />Assistant Professor, Department of Pathology & Molecular Medicine, Queen’s University<br />(SEAMO New Clinician-Scientist Program)</p> </div> </div> </div> </div> </div> </section> <section class="elementor-section elementor-inner-section elementor-element elementor-element-5165eca0 elementor-section-boxed elementor-section-height-default elementor-section-height-default" data-id="5165eca0" data-element_type="section" data-e-type="section"> <div class="elementor-container elementor-column-gap-default"> <div class="elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-3fd304c9" data-id="3fd304c9" data-element_type="column" data-e-type="column"> <div class="elementor-widget-wrap elementor-element-populated"> <div class="elementor-element elementor-element-407ca2ec elementor-widget elementor-widget-image" data-id="407ca2ec" data-element_type="widget" data-e-type="widget" data-widget_type="image.default"> <div class="elementor-widget-container"> <img decoding="async" width="1024" height="683" src="https://netrf.org/wp-content/uploads/2026/01/Nancy-Joseph-1024x683.jpg" class="attachment-large size-large wp-image-44436" alt="" srcset="https://netrf.org/wp-content/uploads/2026/01/Nancy-Joseph-1024x683.jpg 1024w, https://netrf.org/wp-content/uploads/2026/01/Nancy-Joseph-300x200.jpg 300w, https://netrf.org/wp-content/uploads/2026/01/Nancy-Joseph-768x512.jpg 768w, https://netrf.org/wp-content/uploads/2026/01/Nancy-Joseph-1536x1024.jpg 1536w, https://netrf.org/wp-content/uploads/2026/01/Nancy-Joseph-2048x1366.jpg 2048w" sizes="(max-width: 1024px) 100vw, 1024px" /> </div> </div> </div> </div> <div class="elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-3cd1e419" data-id="3cd1e419" data-element_type="column" data-e-type="column"> <div class="elementor-widget-wrap elementor-element-populated"> <div class="elementor-element elementor-element-2b29c776 elementor-widget elementor-widget-text-editor" data-id="2b29c776" data-element_type="widget" data-e-type="widget" data-widget_type="text-editor.default"> <div class="elementor-widget-container"> <p><strong>Nancy Joseph, MD, PhD</strong><br />Professor of Surgical Pathology, University of California, San Francisco (UCSF)</p> </div> </div> </div> </div> </div> </section> <section class="elementor-section elementor-inner-section elementor-element elementor-element-4b06c46e elementor-section-boxed elementor-section-height-default elementor-section-height-default" data-id="4b06c46e" data-element_type="section" data-e-type="section"> <div class="elementor-container elementor-column-gap-default"> <div class="elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-1b6398a1" data-id="1b6398a1" data-element_type="column" data-e-type="column"> <div class="elementor-widget-wrap elementor-element-populated"> <div class="elementor-element elementor-element-49a691b4 elementor-widget elementor-widget-image" data-id="49a691b4" data-element_type="widget" data-e-type="widget" data-widget_type="image.default"> <div class="elementor-widget-container"> <img loading="lazy" decoding="async" width="364" height="508" src="https://netrf.org/wp-content/uploads/2025/02/Dr.- Aman-Chauhan-MD.jpg" class="attachment-large size-large wp-image-40955" alt="" srcset="https://netrf.org/wp-content/uploads/2025/02/Dr.- Aman-Chauhan-MD.jpg 364w, https://netrf.org/wp-content/uploads/2025/02/Dr.- Aman-Chauhan-MD-215x300.jpg 215w" sizes="(max-width: 364px) 100vw, 364px" /> </div> </div> </div> </div> <div class="elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-33515238" data-id="33515238" data-element_type="column" data-e-type="column"> <div class="elementor-widget-wrap elementor-element-populated"> <div class="elementor-element elementor-element-2db765ab elementor-widget elementor-widget-text-editor" data-id="2db765ab" data-element_type="widget" data-e-type="widget" data-widget_type="text-editor.default"> <div class="elementor-widget-container"> <p><strong>Aman Chauhan, MD</strong><br />University of California, San Francisco</p> </div> </div> </div> </div> </div> </section> <section class="elementor-section elementor-inner-section elementor-element elementor-element-5c558a70 elementor-section-boxed elementor-section-height-default elementor-section-height-default" data-id="5c558a70" data-element_type="section" data-e-type="section"> <div class="elementor-container elementor-column-gap-default"> <div class="elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-7dbcec22" data-id="7dbcec22" data-element_type="column" data-e-type="column"> <div class="elementor-widget-wrap elementor-element-populated"> <div class="elementor-element elementor-element-11a2f1d1 elementor-widget elementor-widget-image" data-id="11a2f1d1" data-element_type="widget" data-e-type="widget" data-widget_type="image.default"> <div class="elementor-widget-container"> <img loading="lazy" decoding="async" width="200" height="200" src="https://netrf.org/wp-content/uploads/2026/03/Jerome-Cros-MD-PhD-1.jpeg" class="attachment-large size-large wp-image-45293" alt="" srcset="https://netrf.org/wp-content/uploads/2026/03/Jerome-Cros-MD-PhD-1.jpeg 200w, https://netrf.org/wp-content/uploads/2026/03/Jerome-Cros-MD-PhD-1-150x150.jpeg 150w" sizes="(max-width: 200px) 100vw, 200px" /> </div> </div> </div> </div> <div class="elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-338453b" data-id="338453b" data-element_type="column" data-e-type="column"> <div class="elementor-widget-wrap elementor-element-populated"> <div class="elementor-element elementor-element-49b01d9 elementor-widget elementor-widget-text-editor" data-id="49b01d9" data-element_type="widget" data-e-type="widget" data-widget_type="text-editor.default"> <div class="elementor-widget-container"> <p><strong>Jerome Cros, MD, PhD,</strong><br />Beaujon Hospital, Paris</p> </div> </div> </div> </div> </div> </section> </div> </div> </div> </section> <div class="elementor-element elementor-element-6b423826 e-flex e-con-boxed e-con e-parent" data-id="6b423826" data-element_type="container" data-e-type="container"> <div class="e-con-inner"> <div class="elementor-element elementor-element-37dd650d elementor-widget elementor-widget-text-editor" data-id="37dd650d" data-element_type="widget" data-e-type="widget" data-widget_type="text-editor.default"> <div class="elementor-widget-container"> A special thank you to Paige Corrente for sharing her neuroendocrine cancer journey. </div> </div> <div class="elementor-element elementor-element-2e646c0e elementor-widget elementor-widget-button" data-id="2e646c0e" data-element_type="widget" data-e-type="widget" data-widget_type="button.default"> <div class="elementor-widget-container"> <div class="elementor-button-wrapper"> <a class="elementor-button elementor-button-link elementor-size-sm" href="https://netrf.org/wp-content/uploads/2026/03/NETWise-EP-52-Why-Is-Neuroendocrine-Cancer-on-the-Rise_.pdf" target="_blank"> <span class="elementor-button-content-wrapper"> <span class="elementor-button-text">Download a transcript of this episode.</span> </span> </a> </div> </div> </div> </div> </div> </div> <p>The post <a href="https://netrf.org/podcast/episode-53-understanding-pathology/">Episode 53: Understanding Pathology</a> appeared first on <a href="https://netrf.org">NETRF</a>.</p>
58 total episodes available with 4 transcripts
Recent guests on NETWise
Guests from recent episodes — sign up to see every guest that has ever appeared on this show.
Aman Chauhan
Guest
Nancy Joseph
Guest
Mark Lewis
Guest
Jaydira Del Rivero
Guest
Shari Schutz
Guest
Barbara Dunham
Guest
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