The goal of the Neurocritical Care Society Podcast is to summarize some of the latest content and cutting edge research published in the journal, Neurocritical Care, official journal of the Neurocritical Care Society. Episodes are produced regularly and feature interviews with the top researchers around the world in the fields of neurology, critical care and neurosurgery.
HOT TOPICS: ROTEM Parameters and Hematoma Expansion After Spontaneous Intracerebral Hemorrhage
In this episode of the NCS Podcast Hot Topics series, host Rich Choi, DO, is joined by Ofer Sadan, MD, PhD, neurointensivist at Emory University and associate editor of Neurocritical Care, to discuss the recent study, "Association of Rotational Thromboelastometry Parameters With Hematoma Expansion After Spontaneous Intracerebral Hemorrhage," published in Neurocritical Care.
Their discussion begins with the evolution of coagulation testing and the differences between thromboelastography (TEG) and ROTEM before turning to the study's findings. Among 70 patients, researchers identified an association between clot lysis measurements and hematoma expansion, raising questions about whether subtle changes in coagulation could help predict which patients are most at risk.
Choi and Sadan also consider the study's limitations, the challenges of translating these findings into clinical practice and how future research could help identify patients who may benefit from more targeted interventions.
The views expressed on the NCS Podcast are solely those of the host and guest and do not necessarily reflect the opinions or official positions of the Neurocritical Care Society.
14 Oct 2026
MASTERCLASS: From PRx to the Future of Brain Monitoring
In this Masterclass episode of the Neurocritical Care Society Podcast, hosts Stephan Mayer, MD, FCCM, FNCS, and Jon Rosenberg, MD, sit down with Marek Czosnyka, PhD, Professor of Brain Physics at the University of Cambridge, to discuss his career in brain monitoring and the work that has shaped modern neurocritical care. Professor Czosnyka shares how his early background in biomedical engineering led to research in intracranial pressure monitoring, the development of the pressure reactivity index (PRx) and eventually the concept of optimal cerebral perfusion pressure (CPPopt).
They also discuss cerebral autoregulation, transcranial Doppler and noninvasive ICP monitoring, near-infrared spectroscopy and how these tools can help clinicians better understand what is happening in the brain at the bedside. Professor Czosnyka shares where he sees the field heading next, including the use of artificial intelligence to interpret monitoring data and the potential for closed-loop systems to help guide treatment.
The views expressed on the NCS Podcast are solely those of the hosts and guests and do not necessarily reflect the opinions or official positions of the Neurocritical Care Society
7 Oct 2026
HOT TOPICS: The FASTEST Trial and the Future of ICH Treatment
In this episode of the NCS Podcast Hot Topics series, host Eric Lawson, MD, speaks with Stephan Mayer, MD, about the FASTEST clinical trial and the decades-long effort to determine whether ultra-early hemostatic therapy can improve outcomes for patients with spontaneous intracerebral hemorrhage (ICH). Dr. Mayer shares how the idea of using recombinant factor VIIa in ICH first emerged and how earlier trials helped shape the questions researchers are asking today.
The conversation explores what FASTEST revealed about the relationship between treatment timing, hematoma expansion and functional outcomes — and why identifying the patients most likely to benefit remains so important. Dr. Mayer also discusses the role of the CTA spot sign, the risks that must be weighed with factor VIIa and how lessons from FASTEST are informing the next phase of research.
Drs. Lawson and Mayer also discuss where hemostatic therapy could fit within the Code ICH approach and how advances in imaging and radiomics may help clinicians recognize ongoing bleeding sooner and better target treatment.
The views expressed on the NCS Podcast are solely those of the host and guest and do not necessarily reflect the opinions or official positions of the Neurocritical Care Socie
Who has been a guest on Neurocritical Care Society Podcast
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Tara Wall
Ron Wall
Diane McLaughlin, FNCS
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