
Outperform Cancer
Claim This Podcastby Marybeth Gilliam
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Podcast Overview
<p>Actionable, anti-cancer strategies found in peer-reviewed, scientific research to improve cancer outcomes.</p>
Language
🇺🇲
Publishing Since
9/27/2023
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Recent Episodes

June 18, 2026
Mammograms Save Lives—So Why Are Women Still Diagnosed With Late-Stage Breast Cancer?
In this episode of Outperform Cancer, Marybeth Gilliam speaks with Dr. Ryan Polselli, a fellowship-trained breast imaging radiologist and founder and CEO of MammoLink, about one of the most important questions in breast cancer care: if mammograms save lives, why are women still being diagnosed with late-stage breast cancer? Dr. Polselli explains that the problem is not simply whether mammograms work — it is whether the screening system is working for patients. Too many women are not getting screened annually, dense breast tissue can make cancer harder to detect, genetic risk is often identified only after diagnosis, and unnecessary friction in the healthcare system causes patients to delay or skip screening altogether. The conversation explores how breast cancer detection can become more personalized through annual screening, risk assessment, genetic testing, breast density awareness, AI-supported imaging, same-day ultrasound when appropriate, and better access through mobile mammography. Dr. Polselli also discusses how MammoLink is working to remove barriers by bringing breast imaging directly to workplaces and communities, making screening easier, faster, and more patient-centered. Marybeth also shares her own experience of being diagnosed after insisting on further testing despite a “clear” mammogram, reinforcing one of the episode’s most important messages: women should trust their bodies, understand their risk, and advocate for additional imaging or biopsy when something does not feel right. This episode is a call to rethink breast cancer screening as a strategy — one that uses the tools we already have more effectively to catch cancer earlier, reduce late-stage diagnoses, and help more women get the care they need before it is too late.

June 2, 2026
A New Operating System for Cancer: How Sid Sijbrandij is Outpacing an Evolving Disease
What do you do when you’re told: “There’s nothing more we can do”? That’s the moment Sid Sijbrandij faced after exhausting standard of care for osteosarcoma. Instead of accepting it, he did something radically different. He went “Founder Mode” on his cancer—applying the same mindset he used to build GitLab to create a completely new way of approaching treatment. What emerged isn’t just a set of therapies. It’s a new operating system for cancer—one built on: maximal diagnostics continuous data collection testing treatments in parallel and learning faster than the disease evolves In this episode, we break that system down—not just as Sid’s story, but as a framework patients can start using today. This conversation is not about doing everything Sid has done. It’s about learning how to think differently—so you can ask better questions, access better options, and make more informed decisions about your care. Because cancer isn’t one problem. It’s a system. And when you start treating it that way, everything changes.

May 14, 2026
Can Broccoli Sprouts Fight Cancer? What 30 Years of Research Shows
What if one of the most studied anti-cancer compounds isn’t a drug—but a compound found in broccoli sprouts? In this episode, Jed Fahey, a nutritional biochemist and one of the world’s leading experts on sulforaphane, breaks down over 30 years of research on this powerful compound and its potential role in cancer prevention and treatment. Recent research has taken this conversation to another level. A 2024 review in the journal Cancer found that sulforaphane demonstrates “potent chemosensitizing capabilities across diverse cancer types,” meaning it may help make cancer cells more responsive to chemotherapy while counteracting treatment resistance. In this conversation, we explore: - How sulforaphane works at the molecular level, including its effects on detoxification pathways like NRF2 - Why broccoli sprouts contain dramatically higher levels than mature broccoli - The difference between supplements and whole foods—and what patients should consider - The emerging science around cancer stem cells, metastasis, and recurrence - How sulforaphane may work synergistically with cancer therapies This is not about replacing standard treatment. It’s about understanding how simple, science-backed strategies—like broccoli sprouts—may play a meaningful role alongside it. If you’re looking for actionable, research-driven ways to support your body, this episode translates complex cancer biology into clear, practical insights you can use today.
17 total episodes available
Recent guests on Outperform Cancer
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Kristen Dahlgren
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Frequently asked questions
Have a different question and can't find the answer you're looking for? Reach out to our support team by sending us an email and we'll get back to you as soon as we can.
- What is Outperform Cancer?
<p>Actionable, anti-cancer strategies found in peer-reviewed, scientific research to improve cancer outcomes.</p> - How often does this podcast release new episodes?
This podcast updates bi-weekly.
- Where can I listen to this podcast?
This podcast is available on 8 platforms including Apple Podcasts, Spotify, and more. You can also use the RSS feed directly.
- Does this podcast accept guests?
Yes, this podcast regularly features guests.
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