Join Dr. Kyle Concannon, an MD Anderson–trained cancer doctor and scientist, together with the patient community, as we break down the knowledge and cultural barriers between cancer patients and cancer providers. Cracking Cancer empowers listeners with clear, accessible insights into cancer care, treatment options, and the complex world of cancer. Here, academic experts (providers) and experiential experts (patients) come together to discuss critical topics and build a more informed, supportive cancer community. Join us as we crack the code to better communication, knowledge, and collaboration in the fight against cancer. This podcast is intended for informational purposes only. It does not constitute medical advice and should not be relied upon as such. The views expressed are those of the participants and not of their affiliated organizations.
The Cracking Cancer Podcast
Claim This Podcastby Dr. Concannon and the Patient Community
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Podcast Overview
Join Dr. Kyle Concannon, an MD Anderson–trained cancer doctor and scientist, together with the patient community, as we break down the knowledge and cultural barriers between cancer patients and cancer providers. Cracking Cancer empowers listeners with clear, accessible insights into cancer care, treatment options, and the complex world of cancer. Here, academic experts (providers) and experiential experts (patients) come together to discuss critical topics and build a more informed, supportive cancer community. Join us as we crack the code to better communication, knowledge, and collaboration in the fight against cancer. This podcast is intended for informational purposes only. It does not constitute medical advice and should not be relied upon as such. The views expressed are those of the participants and not of their affiliated organizations.
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Publishing Since
2/13/2025
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Recent Episodes
May 28, 2026
Does Fenbendazole Target Cancer with Dr. Rob Swanda and Samantha Murrell. Episode 54.
Deconstructing Fenbendazole: Scaffolding, Solvents, and the "Joe Tippens" Protocol In this highly requested follow-up to their Ivermectin discussion, host Dr. Kyle Concannon, patient advocate Samantha Murrell, and science communicator Rob Swanda, PhD, touch the hot stove of alternative oncology once again. This time, they dive deep into Fenbendazole (commonly called "Fenben"), an antiparasitic veterinary drug that has exploded in popularity across cancer forums due to the viral "Joe Tippens Protocol." Samantha opens up about her personal choice to take Fenbendazole secretly for eight months alongside conventional chemotherapy, providing an unfiltered look at the immense "what if" pressure patients face behind closed doors. The conversation shifts to rigorous biochemical scrutiny as Dr. Kyle and Rob break down what the drug actually does inside a petri dish and a living organism. They expose the fascinating irony of alternative health branding: while Fenbendazole is frequently marketed online as a "natural, holistic alternative to harsh toxins," it is completely synthetic. Conversely, the very chemotherapies it seeks to replace are the ones derived directly from nature. Moving step-by-step through peer-reviewed data, they analyze how this compound disrupts cellular architecture, why its therapeutic thresholds carry hidden toxicities, and how missing variables in animal models can obscure the difference between a true anti-tumor signal and a general cellular poison. Key Takeaways: The Microtubule Mechanism (Chemo in Disguise) The P53 Gene Context The "Healthy Tissue" Toxicity Flaw Flawed Mouse Models & Missing Data Association vs. Causation Want to get more involved with cancer research and support the podcast? Visit the link below: ⬇️ (All proceeds go strictly towards furthering cancer research and supporting this podcast) Giving.CU.EDU/CrackingCancer For more information on Fenbendazole, check out Rob's info-packed video below! https://youtu.be/DDVko6G84wo Want to see the data yourself? Check out the actual papers below: Fenbendazole acts as a moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways https://pmc.ncbi.nlm.nih.gov/articles/PMC6085345/ Fenbendazole Exhibits Differential Anticancer Effects In Vitro and In Vivo in Models of Mouse Lymphoma https://www.mdpi.com/1467-3045/45/11/560 Chapters: (00:00) Why Fenbendazole Now (01:38) Samantha Tries Fenben (02:09) Joe Tippens Protocol Buzz (04:04) How She Took It (06:14) Social Pressure and Disclosure (08:23) What Fenbendazole Is (11:17) Microtubules and Cancer Logic (13:29) Natural Versus Synthetic Debate (17:25) Preclinical Evidence Deep Dive (19:31) Mouse Study Caveats (25:57) Safety Unknowns and Next Steps (30:39) Paper Rigor Check (31:42) Dose Response Reality (33:15) P53 Dependency Explained (38:25) Healthy Cell Toxicity (40:32) Missing Controls Bias (42:28) Second Study Lymphoma (44:42) Why Immune Free Mice (49:30) How Strong Is Evidence (54:38) Anecdotes Versus Causation (57:00) Mechanism Gaps Takeaways (59:33) Final Verdict Sign Off To find out more about supporting the show and research endeavors, please go to the following website: www.crackingcancer.org Attributions The music track - Progression Pulse - is provided by Denys Brodovskyi through the Attribution 4.0 International License X: (1) Cracking Cancer Podcast (@Cracking_Cancer) / X IG: Cracking Cancer (@crackingcancerpodcast) • Instagram photos and videos
May 21, 2026
Challenges of Rural Cancer Care with Zack Schroeder and J.J. Singleton. Episode 53.
In this critical episode of Cracking Cancer, host Dr. Kyle Concannon reunites with co-host JJ Singleton and welcomes Zach Schroeder, a first-year intern at Wake Forest and the founder of the Rural Cancer Institute. Zach sharing his harrowing personal journey as a 21-year-old diagnosed with Stage III melanoma in a tiny Kansas town anchors the conversation. To receive life-saving surgeries and radiation at MD Anderson, Zach faced an 1100-mile round trip, waking up at 2:00 AM on treatment days to fly across state lines—all while balancing his junior year of college. The trio dives into the staggering statistics defining the "Rural Cancer Gap." They explore the reality that while cancer mortality is declining nationwide, urban survival rates are improving significantly faster than rural ones. From local hospital closures and severe screening shortages (like having only seven providers to perform colonoscopies across a 14-county region in western North Carolina) to systemic medical licensing laws that legally prohibit academic oncologists from billing for telehealth across state lines, this episode exposes the bureaucratic and geographic barriers holding back rural survival. But it also highlights a powerful cultural truth: the profound community support unique to small-town medicine, and how model frameworks like the "Rural Oncology Home" are blending high-tier academic decision-making with local, close-to-home infusion care. Key Takeaways: The Widening Rural Mortality Gap The Telehealth "Billing Wall" The "Rural Oncology Home" Model Severe Screening Deserts The Sibling/Caregiver Strain Want to get more involved with cancer research and support the podcast? Visit the link below: ⬇️ (All proceeds go strictly towards furthering cancer research and supporting this podcast) Giving.CU.EDU/CrackingCancer Chapters: (00:00) Zach Melanoma Journey (08:16) JJ Colon Cancer Travel (10:34) Rural Care Barriers Data (16:35) Rural Cancer Gap Explained (20:45) Rural Oncology Home Model (25:18) Telehealth and Licensing (39:41) Isolation and Culture Shock (49:45) Solutions Training and Teams (53:20) Second Opinions and Support (56:22) Final Advice and Wrap To find out more about supporting the show and research endeavors, please go to the following website: www.crackingcancer.org Attributions The music track - Progression Pulse - is provided by Denys Brodovskyi through the Attribution 4.0 International License X: (1) Cracking Cancer Podcast (@Cracking_Cancer) / X IG: Cracking Cancer (@crackingcancerpodcast) • Instagram photos and videos
May 14, 2026
Does Ivermectin Target Cancer with Dr. Rob Swanda and Samantha Murrell. Episode 52.
Touching the Hot Stove: The Truth About Ivermectin and Cancer In this high-stakes episode of Cracking Cancer, host Dr. Kyle Concannon is joined by patient advocate Samantha Morrell and biochemist Rob, PhD, to dissect the data behind the Ivermectin "miracle cure" narrative. Samantha candidly shares her personal experience with the drug, including the social pressure that led her to try it and the subsequent disease progression she experienced while on it. The conversation moves from social media anecdotes to the hard science of the petri dish. Rob explains the actual mechanism of Ivermectin as an antiparasitic and why the "cancer is a parasite" theory is biologically incorrect. They deconstruct the preclinical studies often cited by proponents, revealing a massive dosing gap: the concentrations required to kill cancer cells in a lab are 10 to 100 times higher than what the human body can safely tolerate. From the dangers of DMSO as a solvent to the ICU-level risks of high-dose toxicity, this episode provides a grounded, peer-reviewed reality check for patients navigating the "what if" pressure of alternative therapies. Key Takeaways: The Dosing Disconnect Cancer is Not a Parasite The Danger of "False Hope" Time-Loss The "Immune Cold to Hot" Myth Repurposing vs. Folklore Want to get more involved with cancer research and support the podcast? Visit the link below: ⬇️ (All proceeds go strictly towards furthering cancer research and supporting this podcast) Giving.CU.EDU/CrackingCancer Want to learn more about Ivermectin? Watch Rob's quick explainer video in the link below! https://youtu.be/gpaowjmeiLc Chapters: 00:00 Why Ivermectin Now02:35 Samantha Tried It04:55 Pressure and Regret06:28 What Ivermectin Is12:32 Why Trials Matter20:31 Doses and Toxicity29:47 Does It Kill Cells34:31 DMSO As Alternative Therapy38:26 Toxicity And Neuro Risks43:18 Glutamate Cancer Metabolism46:41 Why Petri Dish Misleads51:29 If It Worked Pharma Would Pivot53:36 Anecdotes And Missing Case Reports55:41 Self Dosing And False Hope57:44 Wrap Up And Key Takeaways To find out more about supporting the show and research endeavors, please go to the following website: www.crackingcancer.org Attributions The music track - Progression Pulse - is provided by Denys Brodovskyi through the Attribution 4.0 International License X: (1) Cracking Cancer Podcast (@Cracking_Cancer) / X IG: Cracking Cancer (@crackingcancerpodcast) • Instagram photos and videos
54 total episodes available
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- What is The Cracking Cancer Podcast?
- How often does this podcast release new episodes?
This podcast updates daily.
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This podcast is available on 4 platforms including Apple Podcasts, Spotify, and more. You can also use the RSS feed directly.
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