by Daniel Stickler, M.D.
Dr. Daniel Stickler, MD brings you weekly episodes of The Ironman Executive. We explore the world of enhancing human function and performance through advances in science, medicine, and technology. Upgrade your human operating system to Human 2.0 and live the epic life you desire.
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8/3/2014
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November 22, 2017
<p>Our guest for the week is Hyla Cass, an integrative psychiatrist practiced in the field even before the term was coined. Her 25-year long practice is marked by the non-drug, natural system boosting approach, which landed her the nation-wide acclaim along with numerous awards. She is here to talk to us about <strong>the subversive effects of medications, the systems approach to medicine, as well as about enhancing our cognitive performance.</strong></p> <h2>Side-effect Are Still Effects</h2> <p>Stuffing oneself with medication rarely comes without the so-called side-effects. What is important to realize, however, is that the ‘side-effects’ are actually the ‘effects’ of a medication; they are a part of the whole bodily response to, or indeed against, that medication.</p> <p>The purple pill for instance, one of the proton-pump inhibitors, is a fairly available drug that may, in a long run, because the system adjusts and later craves for its usage, cause many hitherto unforeseen and avoidable microbiome problems. Therefore, Instead of forcing the system and suppressing it into an unnatural submission, much more profound effects can be achieved by letting the brain and body work out the problem by themselves.</p> <p><span style="font-size: 12pt;"><em>“the medications upset homeostasis of the brain and can cause more problems than they solve” </em></span></p> <h2>Take a Pill VS. The Systems Approach</h2> <p>Medications are not necessarily bad, but overprescribing them certainly is. Write off a patient with a simple prescription has become the expected doctoral practice nowadays. Much better than the simple pill approach is to, when treating a person, take the whole system into account and boost is. Taking both internal and external factors into consideration, the systems approach goal is to give the body the best possible chance to overcome an issue by itself, mobilizing its own natural resources.</p> <p><strong>Take trauma for instance;</strong> any trauma related disorder can be likened to a program that runs in the back of one’s mind, essentially affecting everything. Taking a pill would solve nothing; we need to clear up the underlying program first before treating an issue. </p> <p> </p> <p><span style="font-size: 14pt;"><strong>“We need to respect what the individual biochemistry is doing @hylacassmd”</strong></span></p> <h2>Endless Charts and Diagrams</h2> <p>Today’s medicine falls into a trap of overcharting the treatment process, neglecting the individuality of each case. Everything is subdued to sort of a medicinal syllogism; a symptom is always followed by a prescribed treatment route which in effect negates the fact that every case is, just as people are, different.</p> <p>The situation is not all that new, it became effective with the branching specialization of medicine, and can be solved by, while of course keeping the specialist medicine, <strong>returning to a more holistic approach to treatment.</strong></p> <h2>Empowering Your Brain</h2> <p>Another field of practice for Dr. Cass that perfectly fits into the systems approach is the cognitive function enhancement. Being the best possible version of ourselves is best achieved through slight, or not so slight lifestyle modifications. Sleep is one factor, diet or exercise another. The exposure to toxins, and the genetic predisposition thereof, may also play a crucial role concerning the quality of life.</p> <h2>Resource Links</h2> <p><a href="%E2%80%9Chttps:/cassmd.com/%E2%80%9D">Dr. Hyla Cass’ Website</a></p> <p><a href= "%E2%80%9Chttps:/www.amazon.com/Supplement-Your-Prescription-Doctor-Nutrition/dp/1591202272%E2%80%9D"> Supplement Your Prescription: What Your Doctor Doesn’t Know About Nutrition</a> <a href= "%E2%80%9Chttps:/cassmd.com/reclaimyourbrain/%E2%80%9D">Reclaim Your Brain Free Ebook</a> <a href= "%E2%80%9Chttp:/www.huffingtonpost.com/author/hyla-cass-md%E2%80%9D"> Dr. Cass’s Articles</a></p>
November 22, 2017
<p>Our guest for the week is Dr. Lucia Aronica, a postdoctoral fellow at Stanford Cancer Center and an expert on epigenetic medicine. Her main focus revolves around genomics of nutrition, that is, the correlation between diet and the changes in epigenetic landscape. Holding a Ph.D. in Molecular Biology, Dr. Aronica has spent the last decade researching the influence lifestyle has on our genomes. Her endeavors landed her not just a few recognitions, Marie Curie Global Fellowship Award being one of them. In this interview, she shares her thoughts on <strong>food, diet, as well as sheds some light on the role epigenetics plays in weight loss.</strong></p> <h2>Not All Food Should be Counted as Such</h2> <p>Coming from Italy, pasta and bread were an inseparable part of Dr. Aronica’s early life. But Mediterranean diet, hailed as it is, accounts for much more that the iconic, yet not so healthy duo. This diet holds precedence over typical ‘western’ diets mainly because of the olive oil, which pitted against omega 3 seed oils, strikes a dashing victory in terms of weight and triglycerides loss. The concept of food is also differently conceived in the Mediterranean diet. The quick fixes are not counted as food in Italy, nor should anywhere else: one has to find the time for some cooking.</p> <h2>Nature and Nurture Working Together</h2> <p>The single best way to attain nutritional health is to strike a steady and sustainable balance. Genetics does play a role and, to an extent, predestine the type of diet a person needs. But, it would be false to assume that our lifestyles do not play their role, for it is they that influence the epigenetic image in our cells. The combination of genetics and lifestyle make each of us different and nutritionally unique. Still, there are a few universals, one of which marks a respective correlation between the decrease in carbohydrates and the decrease of triglycerides. The latter in turn has an effect on cardiovascular risks and the amount of bad cholesterol that strikes the arteries. Lowering the carbs, therefore, plays the role in reducing the risk of atherosclerosis.</p> <h2>The Stanford Studies</h2> <p>Dr. Aronica is currently playing a role in one of the largest studies concerning weight loss. It is a follow-up to an earlier, Stanford A to Z study, where more than 300 women were subjected to four popular diets, (Atkins, Zone, LEARN, and Ornish) measuring their results after one year. At the surprise of many, the very low-carb Atkins diet came out on top in terms of weight loss, cholesterol, and blood pressure. The new study will be bigger, include both men and women, and explore more thorough results like micro-biome and body composition change, as well as the changes in epigenetic landscape. </p> <h2>Epigenetics as a Growing Discipline</h2> <p>Gastric bypass patients yielded significant knowledge regarding the epigenetic research. The different epigenetic image and the weight-loss they experienced after the operation proved that the epigenetic markers are potentially reversible, in this case from ones found in obese to those seen in lean people. These markers may also be transmissible to future generations, but further study is needed to see whether sperm incorporates these epigenetic changes. Epigenetics is a growing branch of medicinal science, today even able to predict the risk of type-2 diabetes. <strong>But what of tomorrow?</strong> The future discoveries are imminent, due to the change in approach. Namely, instead of looking at a few genes or a few hundreds of them, epigenetic researchers, Dr. Aronica among them, are bent towards looking at the entire genome. Also, epigenetic research is determined to explore the DNA in its entirety, including the non-coding regions. It is quite a feat, but the outcomes potentially exceed the effort by a margin.</p> <h2>Resource Links</h2> <p><a href="https://profiles.stanford.edu/lucia-aronica">Dr. Aronica’s Stanford Research profile</a> <a href= "https://med.stanford.edu/news/all-news/2007/03/stanford-diet-study-tips-scale-in-favor-of-atkins-plan.html"> The Stanford A to Z study</a> <a href= "http://nusi.org/science-in-progress/stanford-university/">The Follow-up Study</a></p>
March 1, 2017
<p>Aaron Traywick is the founder at Ascendance Biomedical where they focus on helping people get the treatments and care they need to save their lives. They also specialize in helping fund and facilitate research by taking initial studies off shore before bringing the data back to the FDA. Learn more about this process as well as two studies they're currently working on.<br /> He shares some of the results they're seeing and potential for the industry with this particular treatment for longevity and life extension overall. Enrollment is currently open for trials to test “Bucky-balls” (also known as Fullerene-C60 and “Bucky-balls”) for their capacity to increase lifespan and maximize human performance.</p> <p> </p> <p>Learn more about the Senolytic Treatments we talk about in the interview and sign up to <strong><a href= "http://www.ascendancebiomed.com/senolytics" target="_blank">join the study here</a></strong></p> <p>Apeiron Academy educates and trains Epigenetic Human Potential Coaches in genomic precision wellness and human potential optimization. Get all the details <strong><a href= "http://www.apeiron.academy/" target= "_blank">here</a>.</strong></p> <p><a href="http://www.ascendancebiomed.com/" target= "_blank">Ascendance Biomed</a></p> <p><a href="https://healthspanpolicy.org" target="_blank">Global Healthspan Policy Institute</a></p>
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