The Lead – a weekly journal review podcast that is designed to keep you up to date and informed on the latest publications and hottest topics in electrophysiology. Key takeaways, in-depth interpretations, and informative interviews are all fitted into 15 minute time slots, so that they fit easily into your busy schedule. Click the link below to learn more!
The Lead Podcast presented by Heart Rhythm Society
Claim This Podcastby The Lead Podcast presented by Heart Rhythm Society
5.0(12 reviews)
157 episodes
Updated Daily
Accepts GuestsHas SponsorsLocation 🇺🇸
63
Podcast Authority
BetaGoodBased on show quality, social media presence, reviews, charts, and more
Quality94
Social0
YouTube0
Engagement82
Podcast Overview
The Lead – a weekly journal review podcast that is designed to keep you up to date and informed on the latest publications and hottest topics in electrophysiology. Key takeaways, in-depth interpretations, and informative interviews are all fitted into 15 minute time slots, so that they fit easily into your busy schedule. Click the link below to learn more!
Language
🇺🇲
Publishing Since
7/10/2023
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63
Podcast Authority
BetaGoodBased on show quality, social media presence, reviews, charts, and more
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Engagement82
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Recent Episodes
May 28, 2026
A Discussion of Exercise Capacity and Quality-of-Life Improvements after Catheter Ablation in Patients with Clinically Asymptomatic Persistent Atrial Fibrillation
<p class="MsoNormal">In this episode of The Lead, host Melissa Middeldorp, MPH, PhD, FHRS is joined by Jenelle Dziano, PhD candidate, Clinical Exercise Physiologist and Adrian D. Elliott, PhD for a discussion of the recent journal article, Exercise Capacity and Quality-of-Life Improvements after Catheter Ablation in Patients with Clinically Asymptomatic Persistent Atrial Fibrillation. Together, they explore the study findings and discuss the impact of catheter ablation on exercise capacity and quality of life in patients with clinically asymptomatic persistent atrial fibrillation.</p> <p class="MsoNormal"><strong>Learning Objectives</strong></p> <ul type="disc"> <li class="MsoNormal">Review the key findings from the journal article examining exercise capacity and quality-of-life outcomes after catheter ablation in patients with clinically asymptomatic persistent atrial fibrillation.</li> <li class="MsoNormal">Discuss the potential clinical implications of catheter ablation for patients who may not report traditional atrial fibrillation symptoms.</li> <li class="MsoNormal">Explore the role of exercise capacity and quality-of-life measures in evaluating treatment outcomes for persistent atrial fibrillation.</li> </ul> <p><strong>Podcast Contributors:</strong></p> <p class="MsoNormal">Host: Melissa Middeldorp, MPH, PhD, FHRS</p> <p class="MsoNormal">Guests: Jenelle Dziano, PhD candidate, Clinical Exercise Physiologist and Adrian D. Elliott, PhD</p> <p class="MsoNormal"><strong>Host and Contributor Disclosure(s):</strong></p> <p class="MsoNormal">M. Middeldorp: Nothing to disclose</p> <p class="MsoNormal">J. Dziano: Nothing to disclose</p> <p class="MsoNormal">A. Elliiott: Nothing to disclose</p>
May 21, 2026
The Lead Episode 151: Heart Rhythm 2026 Late-Breaker Coverage: A Discussion of Outcomes of Left Atrial Appendage Closure versus Oral Anticoagulation in Patients with Atrial Fibrillation and Prior Ablation: A Sub-Analysis of the CHAMPION-AF Clinical Trial
<table> <tbody> <tr aria-describedby="author-review-submit-abstract-setion-0"> <td data-label="Value"><br /> This late-breaking sub-analysis from the CHAMPION-AF trial evaluated outcomes of left atrial appendage closure (LAAC) with the WATCHMAN FLX device versus oral anticoagulation in patients with atrial fibrillation who had previously undergone catheter ablation. Investigators found that LAAC provided similar protection against stroke, cardiovascular death, and systemic embolism compared with non-vitamin K oral anticoagulants (NOACs), while significantly reducing non-procedural bleeding events, regardless of prior ablation status. These findings suggest LAAC may be a viable alternative to long-term anticoagulation in select post-ablation AF patients through a shared decision-making approach.</td> </tr> </tbody> </table> <p><br /> <br /> Join Digital Education Committee member Sandeep A. Saha, MD, MS, FHRS and his colleagues Scott C. Brancato, MD, FHRS and Rakesh Gopinathannair, MBA, MD, FHRS for this late-breaking coverage from Heart Rhythm 2026 in Chicago!</p> <p> </p> <p><strong>Learning Objectives</strong></p> <ul> <li>Review the rationale for left atrial appendage closure as an alternative to long-term oral anticoagulation in patients with atrial fibrillation following catheter ablation.</li> <li>Analyze the CHAMPION-AF sub-analysis outcomes comparing LAAC and NOAC therapy with respect to stroke prevention, cardiovascular outcomes, and bleeding risk.</li> <li>Discuss how these findings may influence patient selection and shared decision-making for stroke prevention strategies in post-ablation atrial fibrillation care. </li> </ul> <p> </p> <p><strong>Podcast Contributors<br /></strong><br /> Sandeep A. Saha, MD, MS, FHRS<br /> Scott C. Brancato, MD, FHRS<br /> Rakesh Gopinathannair, MBA, MD, FHRS </p> <p> </p> <p><strong><br /> Host and Contributor Disclosure(s):<br /> <br /></strong></p> <p><strong>S. Brancato</strong></p> <div>Nothing to disclose.<br /> <br /> <br /></div> <div> <div><strong>R. Gopinathannair<br /> <br /></strong></div> <ul> <li>Board/Advisory Committee Membership: Heart Rhythm Society, AltaThera Pharmaceuticals</li> <li>Honoraria/Speaking/Teaching/Consulting: Abbott, Johnson and Johnson, Boston Scientific, Sanofi</li> </ul> </div> <p><strong><br /> S. Saha<br /></strong></p> <ul> <li>Board/Advisory Committee Membership: Medtronic</li> <li>Honoraria/Speaking/Teaching/Consulting: Medtronic </li> </ul>
May 21, 2026
The Lead Episode 152: A Discussion of Outcomes of Left Atrial Appendage Closure versus Oral Anticoagulation in Patients with Atrial Fibrillation and Prior Ablation: A Sub-Analysis of the CHAMPION-AF Clinical Trial (New England Journal of Medicine)
<table> <tbody> <tr aria-describedby="author-review-submit-abstract-setion-0"> <td data-label="Value">This New England Journal of Medicine study from the CHAMPION-AF trial compared left atrial appendage closure (LAAC) using the WATCHMAN FLX device with non–vitamin K oral anticoagulants (NOACs) in 3,000 patients with nonvalvular atrial fibrillation eligible for anticoagulation therapy. The trial found that LAAC was noninferior to NOACs for preventing stroke, cardiovascular death, and systemic embolism, while significantly reducing non-procedural bleeding over three years of follow-up. These findings suggest LAAC may emerge as a viable first-line alternative to long-term anticoagulation in appropriately selected AF patients.</td> </tr> </tbody> </table> <p><br /> Digital Education Committee Member Danesh Kella, MBBS, FHRS discusses this article from the Heart Rhythm Journal that preceded the Heart Rhythm 2026 Late-Breaking Clinical Trial. He is joined in the conversation by Jason T. Jacobson, MD, FHRS, Ammar M. Killu, MBBS, and Gregory M. Marcus, MD, FHRS.</p> <p> </p> <p><strong>Learning Objectives</strong></p> <ul> <li>Describe the rationale for left atrial appendage closure as an alternative to chronic oral anticoagulation in patients with atrial fibrillation after catheter ablation.</li> <li>Review the efficacy and safety outcomes from the CHAMPION-AF sub-analysis comparing LAAC and NOAC therapy in post-ablation AF patients. </li> <li>Discuss patient selection considerations and the role of shared decision-making when choosing stroke prevention strategies following AF ablation. </li> </ul> <p> </p> <p><strong>Podcast Contributors<br /></strong><br /> Danesh Kella, MBBS, FHRS<br /> Jason T. Jacobson, MD, FHRS<br /> Ammar M. Killu, MBBS<br /> Gregory M. Marcus, MD, FHRS </p> <p> </p> <p><strong>Host and Contributor Disclosure(s):<br /> <br /></strong></p> <p><strong>J.T. Jacobson</strong></p> <div> <div>•Board/Advisory Committee Membership: Abbott Medical</div> <div>•Honoraria/Speaking/Teaching/Consulting: Zoll Medical Corporation, Vektor Medical, Inc.</div> <div>•Research: CardioFocus, Inc., Johnson and Johnson</div> <div>•Stocks, Privately Held: Atlas 5D</div> </div> <div> <div><strong>D. Kella<br /> <br /></strong></div> <div>•Honoraria/Speaking/Teaching/Consulting: Zoll Medical Corporation, MBW Spectrum</div> <div><br /> <strong>A. Killu</strong><br /> <br /></div> </div> <div>•Board/Advisory Committee Membership: Boston Scientific</div> <div>•Honoraria/Speaking/Teaching/Consulting: AtriCure, Inc., Abbott, Biosense Webster, Inc., Siemans Healthineers</div> <div>•Research: Boston Scientific, Access Point Technologies<br /> <br /> <strong>G.M. Marcus</strong><br /> <br /> <div>•Honoraria/Speaking/Teaching/Consulting: InCarda Therapeutics</div> <div>•Research: NIH, PCORI, TRDRP</div> <div>•Stocks, Publicly Traded: InCarda Therapeutics</div> </div> <p> </p>
157 total episodes available
Recent guests on The Lead Podcast presented by Heart Rhythm Society
Guests from recent episodes — sign up to see every guest that has ever appeared on this show.
M Middeldorp
Guest
E Chung
Guest
R Lampert
Guest
Michael S Lloyd
Guest
Hakeem Ayinde
Guest
Prashant Bhave
Guest
Louise Segan
Guest
Takanori Yamaguchi
Guest
Prashanthan Sanders
Guest
Jenish Shroff
Guest
Pugazhendhi Vijayaraman
Guest
Melissa E. Middeldorp, MPH, PhD
Guest
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- What is The Lead Podcast presented by Heart Rhythm Society?
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