Episode 16: Low Flow, High Risk by SPECT: Closing the Access Gap
This episode of JNC CardioConnect explores whether myocardial flow reserve measured by CZT SPECT can match PET’s prognostic value — a key question given how limited PET access is worldwide. Dr. Marcelo Di Carli , Editor-in-Chief of the JNC, speaks with authors Maria Victoria Carvelli, MD and Alejandro Meretta, MD along with Terrence Ruddy, MD, MASNC, about the findings and the practical future where SPECT quantification of myocardial blood flow could help us mitigate the limited access to PET throughout the world.
22 Jun 2026
Episode 15: One Tracer, All Amyloid: The Evuzamitide and REVEAL Story
This episode of JNC CardioConnect explores a new JNC study showing that ¹²⁴I-evuzamitide PET/CT can detect cardiac involvement in rare amyloidosis subtypes that conventional imaging often misses. Editor-in-Chief, Marcelo Di Carli, MD, MASNC speaks with authors Olivier Clerc, MD, MPH and Sharmila Dorbala, MD, MPH, MASNC about the findings, the limitations of today's bone-tracer-based diagnostic approach, and what Bayer's recently announced positive Phase 3 REVEAL results could mean for a future pan-amyloid diagnostic strategy.
21 May 2026
Episode 14: Compendium on Cardiac Amyloidosis: Pathophysiology, Imaging, and Contemporary Management
In this special episode of JNC CardioConnect, Editor-in-Chief, Marcelo Di Carli, MD, MASNC is joined by Omar F. Abou Ezzeddine, MD, MS, Prem Soman, MD, PhD, MASNC, Sharmila Dorbala, MD, MPH, MASNC and Ahmad Masri, MD, MS to discuss the rapidly evolving landscape of cardiac amyloidosis — from the biology that explains what we see on imaging, to best practices in cardiac amyloid radionuclide scintigraphy, the promise of amyloid-targeted PET tracers, and the emerging novel therapies. A rich and forward-looking conversation that covers both where the field stands today and where it's headed. Access the full compendium available open access on the JNC website.
24 Apr 2026
Episode 13: Closing the Gap: Why PET Imaging May Finally Get Heart Disease Diagnosis Right for Women
Women with heart disease have long been underserved by the very tools designed to diagnose them, but that may be changing. In this episode, Editor-in-Chief, Marcelo Di Carli, MD, MASNC is joined by Stephen Horgan, MB, BCh PhD, FASNC, Jamshid Maddahi, MD, MASNC, and Panithaya Chareonthaitawee, MD, MASNC and break down a landmark sub-study from the Aurora trial showing that F-18 flurpiridaz PET significantly outperforms traditional SPECT imaging in detecting obstructive coronary artery disease in women, with higher accuracy, better image quality, and nearly half the radiation dose. The conversation goes further, exploring how quantifying actual blood flow with PET could unlock diagnoses that have eluded clinicians for years, particularly for the many women whose symptoms stem not from blocked arteries, but from microvascular disease. Read the article.
8 Jan 2026
Episode 12: Cardiovascular Imaging Training at an Inflection Point
In this episode, Editor-in-Chief Marcelo F. Di Carli, MD, MASNC leads a timely conversation on the future of cardiovascular imaging training with Ron Blankstein, MD, FASNC and Lawrence Phillips, MD, MASNC. The conversation unpacks the new ACC-sponsored advanced imaging training statement and why multimodality competency is essential for nuclear cardiologists seeking to remain clinically relevant in a world of disease-centered imaging.
14 Nov 2025
Episode 11: SPECT MPI 2.0
Marcelo Di Carli, Yufan Gu, Lei Wang, and Panithaya Chareonthaitawee explore a novel perfusion radiotracer, 4-BOH, and its potential to revolutionize SPECT myocardial perfusion imaging through advancements in tracer chemistry and detector technology in this interview.
7 Nov 2025
Episode 10: The Missing Link Between Imaging Results and Patient Management
Editor Marcelo Di Carli interviews Doctors Krishna Patel and John Spertus about patient-centered reporting, which transforms diagnostic imaging into actionable insights for clinicians and patients.
22 Aug 2025
In a Heartbeat: Episode 9
Editor-in-Chief Marcelo F. Di Carli, MD, MASNC, interviews Daniel M. Huck, MD, MPH, Cesia Gallegos-Kattán, MD, MHS, FASNC, Olivier F. Clerc, MD, MPH, Bruno Bezerra Lima, MD, PhD, and Attila Feher, MD, PhD, discussing key nuclear cardiology research findings and their clinical implications.
15 Aug 2025
Episode 8: When normal SPECT isn’t reassuring—Rethinking risk in exercise SPECT
Marcelo F. Di Carli, MD, MASNC interviews Steven C. Scherping, III, MD, Jamieson M. Bourque, MD, MHS, FASNC, and Diana M. López, MD about new evidence revealing hidden risks in exercise SPECT imaging.
2 Jul 2025
Episode 7: Using Hybrid SPECT/CT Imaging to Guide Patient Management
Waseem Hijazi and Robert JH Miller discuss with Marcelo F. Di Carli how hybrid SPECT/CT imaging enhances risk stratification and tailors medical therapies for CAD patients, potentially improving clinical outcomes in this interview episode.
6 May 2025
Episode 6: Flow Reserve and the Hidden Timeline of Vascular Health
In this episode, Editor-in-Chief Marcelo F. Di Carli, MD, MASNC, is joined by Daniel S. Berman, MD, MASNC and Donghee Han, MD, from the Cedars Sinai Medical Center, to discuss their manuscript ‘Independent prognostic significance of myocardial flow reserve over coronary artery calcium, myocardial perfusion, and clinical variables in patients without known coronary artery disease, according to diabetes status’ and explore the intersection of vascular health, cardiometabolic disease, atherosclerosis and advanced cardiovascular imaging. They examine new evidence about the challenges that traditional boundaries between metabolic health and vascular risk pose to our field.
27 Mar 2025
Episode 5: JNC Compendium: F-18 Flurpiridaz PET Myocardial Perfusion Imaging with Panithaya Chareonthaitawee, MD, Krishna Patel, MD, MS, FASNC, and Rob S.B. Beanlands, MD, MASNC
In this episode, Editor-in-Chief Marcelo F. Di Carli, MD, MASNC, is joined by leading experts Panithaya Chareonthaitawee, MD, from the Mayo Clinic, Krishna Patel, MD, MS, FASNC, from the Icahn School of Medicine at Mount Sinai, along with Rob S.B. Beanlands, MD, MASNC, from the University of Ottawa Heart Institute, to discuss the JNC Compendium on Flurpiridaz PET Myocardial Perfusion Imaging. This episode dives deep into the transformative changes in radionuclide myocardial perfusion imaging and the potential role of flurpiridaz PET in this evolution. Discover the potential benefits of flurpiridaz for improving access to cardiac PET and expanding its clinical use. Our expert guests share insights on the many opportunities and offer their thoughts on how to tackle potential challenges. Do not miss it! Read the Compendium
20 Feb 2025
Current practices and trends in amyloidosis imaging with bone-avid tracer cardiac scintigraphy with Jamieson M. Bourque, MD, MHS, FASNC, Sarah AM. Cuddy, MD, FASNC, and Nishant Shah, MD, MPH, FASNC
In this episode, Editor-in-Chief Marcelo F. Di Carli, MD, MASNC is joined by leading experts Jamieson M. Bourque, MD, MHS, FASNC from the University of Virginia and Sarah AM. Cuddy, MD, FASNC from the Brigham and Women’s Hospital along with Associate Editor, Nishant Shah, MD, FASNC, from the Brown University Alpert Medical School to discuss the evolving role of imaging in diagnosing cardiac amyloidosis.
The conversation focuses on a recent JNC paper analyzing survey data from ASNC on the adoption of radionuclide imaging for ATTR cardiac amyloidosis. The conversation highlights key findings, including shifts in imaging protocols, the growing role of nuclear medicine specialists, and the need for continuous education to ensure high-quality diagnostic standards.
They also discuss the future of the field, including the transition to SPECT/CT, potential PET applications, and the importance of national registries to track clinical outcomes. Read the article.
28 Jan 2025
Episode 3: Effect of Imaging Timing on the Assessment of Treatment Response in Cardiac Sarcoidosis with Chaitanya Rojulpote, MD, Paco E. Bravo, MD, and Sanjay Divakaran, MD, FASNC
In the third episode of JNC CardioConnect, Journal of Nuclear Cardiology (JNC) Editor-in-Chief Marcelo F. Di Carli, MD, MASNC, speaks with Chaitanya Rojulpote, MD and Paco E. Bravo, MD from the Hospital of the University of Pennsylvania, along with Associate Editor, Sanjay Divakaran, MD, FASNC, from the Brigham and Women's Hospital about the article, Assessing the effect of repeat positron emission tomography imaging on treatment response and cardiovascular outcomes among a homogenously treated cohort of patients with suspected cardiac sarcoidosis, published recently in the JNC.
13 Dec 2024
Episode 2: The Changing Landscape of Cardiac Imaging
Radionuclide perfusion imaging remains the dominant force in coronary artery disease assessment, with SPECT leading the charge and PET on a steady rise. In this episode of JNC CardioConnect, Journal of Nuclear Cardiology (JNC) Editor-in-Chief Marcelo F. Di Carli, MD, MASNC, speaks with physicians at Houston Methodist Hospital to discuss their recent article and break down the latest Medicare data, highlighting usage trends in cardiac imaging, underutilized opportunities with PET/CT and myocardial blood flow, and what it all means for the future of cardiac imaging.
19 Nov 2024
Episode 1: Role of Quantitative Radionuclide Imaging in Cardiac Amyloidosis
In the first episode of JNC CardioConnect, Journal of Nuclear Cardiology (JNC) Editor-in-Chief Marcelo Di Carli, MD, MASNC, speaks with Sharmila Dorbala, MD, MASNC, Director of Nuclear Cardiology at the Brigham and Women’s Hospital and Professor of Radiology and Medicine at Harvard Medical School, about the article, Quantitative 99mTc-pyrophosphate myocardial uptake: Changes on transthyretin stabilization therapy, published recently in the JNC, and her extensive research in cardiac amyloidosis.
Who has been a guest on JNC CardioConnect
Names identified in recent episode analyses. Showing up to five guests.
Marcelo Di Carli
Yufan Gu
Lei Wang
Panithaya Chareonthaitawee
Krishna Patel
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Apple Podcasts (US)
5.0 / 5
5 ratings
Spotify
5.0 / 5
1 ratings
Podcast Authority Score: 12 / 100
A composite of feed quality, social presence, YouTube performance and engagement. Read the methodology.
Quality
10
Social presence
0
YouTube
0
Engagement
32
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