Where can I listen to this podcast?

This podcast is available on 4 platforms including Apple Podcasts, Spotify, and more. You can also use the RSS feed directly.

Does this podcast accept guests?

No, this podcast does not typically feature guests.

Peptides Explained

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by John Garrett

4.8(17 reviews)

21 episodes

Updated Daily

Accepts GuestsHas Sponsors

Podcast Overview

Peptides Explained breaks down the most talked-about peptides and GLP-1 medications in health, fitness, and longevity — including semaglutide, tirzepatide, BPC-157, TB-500, and more. Hosted by Registered Nurse John Garrett, this podcast explains how these compounds work, why they’re popular, what the research shows, and the real risks and side effects — all in plain language. No bro science. No hype. Just clear, foundational education. For informational purposes only. Not medical advice. For Research Peptides; Offlinepeptides.com/ref/johngarrett/ https://www.skool.com/peptides-explained-15

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Publishing Since

2/22/2026

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Recent Episodes

June 10, 2026

KPV Explained: Gut Inflammation, Ulcerative Colitis, and the Science Behind the KLOW Blend

In this episode of Peptides Explained, we take a deep dive into KPV, a three-amino-acid peptide derived from alpha-melanocyte stimulating hormone (alpha-MSH) that has generated growing interest for its potential anti-inflammatory effects.We explore the biology behind KPV, how it may influence inflammatory pathways such as NF-kB, and why researchers have studied it in models of ulcerative colitis, Crohn's disease, inflammatory bowel disease (IBD), and intestinal barrier dysfunction.You'll learn:• What KPV is and where it comes from • How KPV may reduce inflammatory signaling • The role of PepT1 transporters in the gut • What animal and laboratory studies have shown • The limitations of current human data • Why KPV has become popular in gut health discussionsWe also examine the growing interest in the KLOW Blend, a combination of:• KPV • BPC-157 • TB-500 • GHK-Cuand discuss the scientific rationale behind combining these peptides to target inflammation, tissue protection, cellular migration, and regeneration.As always, we separate biological mechanisms from marketing claims and review what the evidence actually shows.Peptide Solutions is owned and operated by host John Garrett and helps educate both patients and healthcare professionals about peptide science and peptide therapy pathways.Learn more at:Peptide-Solutions.infoPeptides Explained is an affiliate partner with OfflinePeptides.com.If you use the link below, I may earn a commission at no additional cost to you:<a href="https://offlinepeptides.com/ref/JohnGarrett/">https://offlinepeptides.com/ref/JohnGarrett/</a>Healthcare providers interested in prescribing compounded peptides and individuals interested in telehealth consultation options can learn more through Peptide Solutions.Visit:Peptide-Solutions.infoDisclaimer: This podcast is for educational and informational purposes only and is not medical advice. KPV and the KLOW Blend are not FDA-approved therapies, and much of the research discussed comes from laboratory and animal studies. Always consult a licensed healthcare professional regarding medical decisions.Powered By Peptide SolutionsResearch Peptide Affiliate DisclosureCompounded Peptide Information

June 8, 2026

Selank vs Semax: The Russian Peptides for Anxiety, Focus, and Brain Health

In this episode of Peptides Explained, we take a deep dive into two of the most talked-about Russian research peptides: Selank and Semax.We'll explore where these peptides came from, how they work in the brain, and why researchers have studied them for anxiety, stress resilience, cognitive performance, neuroprotection, and stroke recovery. You'll learn about key mechanisms involving GABA, dopamine, serotonin, BDNF, and neuroplasticity while separating scientific evidence from internet hype.We also review the available clinical data, discuss regulatory status in the United States, and explain what is known—and still unknown—about the safety and effectiveness of these compounds.Whether you're a clinician, researcher, peptide enthusiast, or simply curious about emerging neuroscience, this episode provides a balanced, evidence-based look at Selank and Semax.Topics Covered: • What are Selank and Semax? • Russian peptide research history • Anxiety and stress-response signaling • BDNF and neuroplasticity • Cognitive enhancement claims • Stroke recovery research • Safety considerations and limitations • Current regulatory statusSupport the PodcastPeptides Explained is powered by Peptide Solutions, owned and operated by John Garrett.For educational information about peptides and available options:Peptide Solutions: <a href="" target="_new" rel="noopener">https://peptide-solutions.info</a>For those interested in research-use peptides:<a href="" target="_new" rel="noopener">https://offlinepeptides.com/ref/JohnGarrett/</a>Affiliate Disclosure: Peptides Explained is an affiliate partner with OfflinePeptides.com. If you use the affiliate link above, I may earn a commission at no additional cost to you.This podcast is for informational and educational purposes only and does not constitute medical advice.

June 3, 2026

Can Peptides Help Menopause? The Truth About Libido, Weight Gain & Aging

In this special episode of Peptides Explained, we're focusing on a topic that affects millions of women but often isn't discussed openly enough: menopause, hormonal signaling, libido, body composition, and the emerging role of peptides.Why does weight gain seem different during menopause? What causes the sudden changes in energy, sleep, skin, hair, and sexual desire? And where do peptides like Kisspeptin, PT-141 (Bremelanotide), Tesamorelin, GHK-Cu, BPC-157, and GLP-1 medications fit into the conversation?Join host John Garrett, RN, as he breaks down the science behind female hormone signaling in clear, understandable language. We'll explore the biology of menopause, the neurochemistry of desire, the "collagen cliff," metabolic changes, and the latest research on peptides being studied for women's health and aging.This episode covers: • Menopause and metabolic changes • GLP-1 medications and weight management • Kisspeptin and reproductive hormone signaling • PT-141 and female sexual desire • Tesamorelin and growth hormone pathways • GHK-Cu and collagen production • BPC-157 and recovery science • Oxytocin and emotional connection • What is evidence-based vs. what remains experimentalWhether you're navigating perimenopause, menopause, or simply interested in understanding how peptide science intersects with women's health, this episode delivers a balanced, evidence-based look at one of the most important conversations in modern medicine.Learn more: <a href="http://www.peptide-solutions.info/">www.peptide-solutions.info</a>Podcast website: <a href="http://www.peptidesexplained.info/">www.peptidesexplained.info</a>Support the podcast and learn more about peptide research: offlinepeptides.com/ref/JohnGarrettAffiliate Disclosure: Peptides Explained is an affiliate partner with Offline Peptides. If you use my affiliate link, I may earn a commission at no additional cost to you.Follow Peptides Explained: • Instagram: @PeptidesExplained • Facebook: Peptides Explained • LinkedIn: Peptides Explained • Patreon: Peptides Explained • Skool: Peptides Explained CommunityIf you enjoy the show, please follow, subscribe, leave a review, and share this episode with someone who would benefit from understanding the science behind menopause, hormones, and peptide therapy.Peptides Explained is powered by Peptide Solutions, founded and operated by John Garrett, RN, providing education on peptide science and helping connect patients and clinicians with peptide-related resources.This podcast is for informational purposes only and is not medical advice.

21 total episodes available

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Frequently asked questions

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What is Peptides Explained?: Peptides Explained breaks down the most talked-about peptides and GLP-1 medications in health, fitness, and longevity — including semaglutide, tirzepatide, BPC-157, TB-500, and more.

Hosted by Registered Nurse John Garrett, this podcast explains how these compounds work, why they’re popular, what the research shows, and the real risks and side effects — all in plain language.

No bro science. No hype. Just clear, foundational education.

For informational purposes only. Not medical advice.

For Research Peptides; Offlinepeptides.com/ref/johngarrett/ https://www.skool.com/peptides-explained-15
How often does this podcast release new episodes?: This podcast updates daily.
Where can I listen to this podcast?: This podcast is available on 4 platforms including Apple Podcasts, Spotify, and more. You can also use the RSS feed directly.
Does this podcast accept guests?: No, this podcast does not typically feature guests.

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